Abstract
Obesity is a condition where a person has accumulated so much body fat that it might have a negative effect on their health. Body mass index is a statistical measurement derived from height & weight BMI between 18.5 & 25 kg/m2 indicate a normal weight. BMI of 25-29.9 is considered over weight& that of 30 kg/m2 or above is considered obese. High BMI now ranks with major global health problems like high cholesterol, high blood pressure, in total global burden of disease. For people with obesity, weight loss based solely on life style change in very challenging [2,3] oxidative stress is essential an imbalance between the production of free radicals & obesity of the body to counteract or detoxify their harmful effects through neutralization by antioxidant. Present study was carried out on 1000 subjects 650 were Rajasthani & 350 were south Indian. We divided them further according to BMI and obesity indices. They were than estimated for MDA before consuming fibres diet.MDA was also estimated after 30 days consumption and results were statistically evaluated. [6] BMI & various other indices of obese like waist circumference, hip circumference, waist hip ratio are considered as screening tools for overweight & obese. Oxidative stress increased with increased BMI. Dietary effect showed significant drop in all three categories of BMI (P<0.001).
Keywords: MDA, WHR, BMI, Fibre, Obesity.
References
- C.Tungland, and D.Meyer. Nondige-stible oligo and polysaccharides, their role in human health. Food Science 2002; 173-89.
- Ferraro S, Perrone-Filardi P, Desiderio A, Betocchi S, D’Alto M, Liguori L, Trimigliozzi P, Turco S, Chiariello M (1996): Severe obesity: a radionuclide study. Cardiology; 87: 347–353.
- Fukushige T, Yoshinaga M, Shimago A, Nishi J, Kono Y, Nomura Y, Miyata K, Imamura M, Shibata T, Nagashima M, Niimura I (2002): Effect of age on overweight.Am J Cardiol; 89: 395–398.
- Hirsch J, Leibel RL, Mackintosh R, Aguirre A [1991]: Weight change in humans. Am J physiol;261: R1418-R1423
- K. Reddy, R Ramamurty, and Papa Rao. Free radical and antioxidant status in urban and rural Tirupati men, Asia Pacific J Clin nutr 1997;6: 296-311.
- Kaneria Y, Singh P, Sharma DC (2006): Prevalence of overweight and obesity in relation to socio economic conditions in two different groups of school age children of Udaipur city (Rajasthan). JIACM; 7(2): 133-5.
- Peiris AN, Thakur RK, Sothmann MS, Gustafson AB, Hennes MI, Wilson CR, Kissebah AH.. Relation of regional fat distribution and obesity. South Med J 1991; 84: 961–5.
- Qatanani M and Lazar MA [2007]: Mechanism of obesity. Genes Dev;21: 1443-1455.
- Singh SP, Sikri G, Garg MKBody mass index and obesity; Tailoring cut off for an Asian Indian male population. MJAFI 2008; 64: 350-3.
- Stephan JL, Richard G, Tom Teerlink Hans V, Reinold OB, Robert J (2000) : Cytosolic triglycerides and oxidative stress in central obesity. Atherosclerosis 148: 17-21.
- Streicher R, Kotzka J,Muller-Wieland D, Siemeister G, Munck M, Avci H, Krane W [1996] :Insulin like growth factor-1,Journls of biological chemistry 271:7128-7133.
- Van Itallie TB.Dietary fiber and obesity: American Journal of Clinical Nutrition 1978; 31: S43-52.
Corresponding Author
Shubham Jain
PG Student Department of Biochemistry PMCH Udaipur
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