Abstract
Background: Imprint is a touch preparation in which tissue is touched on the slide and it leaves behind its imprint in the form of cells on glass slide; studies are made after proper staining.
Aims & Objective: (1) To evaluate utility of imprint smears as diagnostic modality;
(2) To correlate the findings of imprint smears with histopathological findings.
Materials and Methods: This was a prospective study of 33 surgical specimens submitted in Department of Pathology, RNT, medical college, Udaipur. Smears obtained were stained with MGG Stain & studied.
Results: Out of total 33 cases of thyroid lesions, 29 were true benign, 03 cases were true malignant and 01 case was falsely diagnosed as benign.
Conclusion: Imprint smear is rapid technique for intraoperative diagnosis & can be utilized as an adjuvant to histological diagnosis.
Keywords: Imprint Smear, thyroid lesions, intraoperative diagnosis, adjuvant
References
- Bal MS, Kahlon SK, Bidani R. Comparative evaluation of aspiration cytology and preoperative imprint cytology in breast lesions. J of Cytology 2000;17:27-32
- Vemuganti GK, Naik MN, Honavar SG, Sekhar GC. Rapid intraoperative diagnosis of tumors of the eye and orbit by squash and imprint cytology. Ophthalmology 111; 1009-15, 2004.
- LiVolsi VA: Postpartum thyroiditis: the pathology slowly unravels [editorial]. Am J Clin Pathol; 100:193-195,1973
- Welker M., Orlov D. Thyroid nodules. American Family Physician. 67 (3): 120-125, 2003.
- Tribe CR. A comparison of rapid methods including imprint cytodiagnosis for the diagnosis of breast tumors. J Clin Pathol; 26: 273–7, 1973.
- Rangaswamy M ,Narendra KL,Patel S, Guruprasad C, Manjunath GV; Insight to neoplastic thyroid lesion by fine needle aspiration cytology.J Cytol.2013;30(1):23
- Aahana Gupta ,Durga Shankar, Jaipal, Sunita Kulhari, Neelu Gupta; Histopathological study of thyroid lesions and correlation with ultrasonography and thyroid profile in Western Zone of Rajasthan .International Journal of Research in Medical Sciences.
- Singh P,Chopra R,Calton N,Kapoor R.Diagnostic Accuracy of Fine Needle Aspiration Cytology of Thyroid Lesion. Journal of Cytology, 2000;17(3);135-9.
- Jimmy Antony, T M Celine ,Michale Chacko. Spectrum of thyroid disorders :A retrospective study at a medical college hospital.2014;11(2);55-59.
- Islam R,Ekramuddaula AFM ,Alam MS,Kabir MS,Hossain D, Alauddin M.Frequency and pattern of malignancy in solitary thyroid nodule.Bangladesh J of otorhinology .2009;15(1):1-5.
- Sangali G,Sergio G,Zampatti C, Bellotti M ,Lomuscio G.Fine needle aspiration cytology of the thyroid :A comparison of 5469 cytological and final histological diagnosis . Cytopathology 2006;17(5):245-50.
- Mandal S , Barman D ,Mukherjee A, Saha J, Sinha R .Fine needle aspiration cytology of thyroid nodules ,evaluation of its role in diagnosis and management .J Indian Medical Association .2011;109(4):258-61.
- Krukowkski ZH. The thyroid gland and thyroglossal tract .In: Williams. NS, Bulstrode CJK, O’Conell PR eds. Baily and Love’s short practice of surgery 24th ed .London.Hodder education .2004:776-804.
- Francis IM, Das DK. Role of FNA, intraoperative cytology and frozen section in the diagnosis of breast lumps and thyroid lesions. Int J Kuwait Univ Health Sci Cent ;8:173-82,1999.
- Pustaka, I.G N,Sudarsa, I W, and Golden, N Diagnostic validity of cytological imprint in thyroid follicular neoplasm .Bali Medical Journal (BMJ) 2013, Volume 2, Number 3: 113-116 P –ISSN . 2089-1180,E-ISSN.2302-2914.
- Taneri F., Poyraz A., Salman B., Tekin E., Onuk E. 'Using imprint and frozen section in determining strategies for thyroid pathologies.' Endocrine regulations. 35:71-75,2001.
- Mutaharra H.A., Deva W., Wani K.A., Wani N.A., Shah A., Malik A.A, Imprint cytology versus frozen section in the intraoperative diagnosis of thyroid swellings, JK practitioner. 8 (1): 27-29,2001.
- Sukumar Shaha ,AJENahar Rahman. Comparative Study of imprint cytology and frozen section in the intraoperative diagnosis of thyroid lesions .Bangladesh S Pathol ;24:12-15,2009.
Corresponding Author
Dr Pupul Bose
RNT Medical College, Udaipur