Malignant Phyllodes Tumour of Breast: Case Report and Review of Literature

Title: Malignant Phyllodes Tumour of Breast: Case Report and Review of Literature

Authors: Dr Narendra Nikam, Dr Alizaid Anwar, Dr Tejas Nikumbh, Dr Sandeep Darbastwar

DOI: https://dx.doi.org/10.18535/jmscr/v5i9.105

Abstract

Phyllodes tumors are rare fibroepithelial breast tumors, which are sometimes difficult to preoperative diagnoses and have unpredictable clinical outcome. Malignant transformation of phyllodes is extremely rare. These tumors must be suspected in patients with rapid-growing breast nodules, with a history of local recurrences to avoid inappropriate management.

We report a case of a large phyllodes tumour of breast with malignant transformation in a 45 year old lady.

References

Liang MI, Ramaswamy B, Patterson CC, McKelvey MT, Cordillo G, Nuovo GJ, Carson WE., III Giant breast tumors: surgical management of phyllodes tumors, potential for reconstructive surgery and review of literature. World Jr of Surgical Oncology. 2008;6:117. doi: 10.1186/1477-7819-6-117
Khan SA, Badve S. Phyllodes tumors of breast. Curr Treat options Oncol. 2001;2:139–147. doi: 10.1007/s11864-001-0056-y.
Tan P-H, Jayabaskar T, Chuah K-L, Lee H-Y, Tan Y, Hilmy M, et al. Phyllodes tumors of the breast the role of pathologic parameters. Am J Clin Pathol. 2005; 123:529–540. doi: 10.1309/U6DVBFM81MLJC1FN.
Rowell MD, Perry RR, Jeng-Gwang H, Barranco SC. Phyllodes tumors. Am J Surg. 1993;165:376–79. doi: 10.1016/S0002-9610(05)80849-9.
Erhan Y, Zekioglu O, Ersoy O, Tugan D, Aydede H, Sakarya A, Kapkaç M, Ozdemir N, Ozbal O, Erhan Y. p53 and Ki-67 expression as prognostic factors in cystosarcomaphyllodes. Breast J. 2002;8(1):38–44. doi: 10.1046/j.1524-4741.2002.08008.x
Kim JH, Choi YD, Lee JS, Lee JH, Nam JH, Choi C et al. Borderline and malignant phyllodes tumors display similar promoter methylation profiles. Virchows Arch 2009;455:469-75.
Bellocq JP, Magro G. Fibroepithelial tumors. In: Tavassoli FA, Devilee P, editors. World health organization classification of tumors: tumors of the breast and female genital organs. Lyon: IARC; 2003. p.99-103.
Grabowski J, Salzsrein SL, Sadler GR, Blair SL. Malignatphylodes tumors: a review of 752 cases. Am Surg2007; 73:967-9.
Goel NB, Knight TE, Pandey S, Riddick-Young M, Paredes ES, Trivedi A. Fibrous lesions of the breast: imaging-pathologic correlation. Radiographics2005;25:1547-59.
Aguillar VLN, Bauab SP, Maranhão NM. Mama: diagnósticoporimagem. Rio de Janeiro: Revinter; 2009.
Uchman P, Samulak D, Wilczak M, Mich-alska MM, Mojs E, Sajdak S. Difficulties in diagnosing and treating phyllodes tumor of the breast – case report. Eur J GynaecolOncol2011;32:111-3.
Jones A.M., Mitter R., Poulsom R. mRNA expression profiling of phyllodestumours of the breast: identification of genes important in the development of borderline and malignant phyllodestumours. J. Pathol. 2008;216(December (4)):408–417.
Islam et al.The largest and neglected giant phyllodes tumor of the breast—A case report and literature review 10.1016/j.ijscr.2016.07.022
Takenaka et al giant phyllodestmour case report ,Kurume me J .2011;58(2):67-72
Tarunkumar et al , largest phyllodes-tumour a case report ,indian journal of oncology ,2011jun 2(2):141-144
Sedigheh et allargephyllodestumour a case report ,middle east jounal of cancer 2013;4(4): 181-184.

Call For Paper Volume 12 Issue 12 December 2024

The JMSCR is accepting manuscripts for its coming issues to be Publish Volume 12 Issue 12 December 2024 the JMSCR invites authors to submit manuscripts Reporting original medical research, original article, research article, case report, systematic reviews, or educational Innovations for publication for the coming issues that will be released in Volume 12 Issue 12 December 2024. Types of manuscripts suitable for JMSCR include: Medical research, Clinical research Educational Innovation, Brief Report, Reviews on Teaching In keeping with high quality scholarship, Read More.....

https://jmscr.igmpublication.org/ems/index.php/jmscr/about/submissions

If any difficulty you can also submit to: This email address is being protected from spambots. You need JavaScript enabled to view it.

JMSCR Menu

Impact Factor SJIF 2024: 7.892

https://sjifactor.com/passport.php?id=1725

Crossref - DOI

Crossref - DOI Prefix: 10.18535/jmscr

Editorial Policy

Authors should prepare their manuscripts according to the instructions given in the authors' guidelines. Manuscripts which do not ..

Frequency of Publication

JMSCR is published as monthly journal with 12 issues per year. Special editions are also planned subjected to the scope and need....

Submission of Articles

Authors are invited to submit their research articles, review papers, Case Report properly formatted as per the author guidelines.........

Search