Abstract
Background: Lung cancer is the most common cause of cancer related death worldwide. Early diagnosis is critical for initiation of specific therapy.
Aim and Objective: To study yield of various procedures in diagnosis of lung cancer.
Material and Methods: This prospective observational study was carried out at a tertiary care centre between December 2010 to august 2012. Total 60 patients presenting with clinical and radiological features suggestive of lung malignancy were studied. sputum cytology were done in all patients. Fibreoptic bronchoscopy, CT guided FNAC, pleural fluid cytology and biopsy were done in patients as per indication by the site of lesion.
Results: Sputum cytology was positive in 5 (8.33%) of patients. BAL cytology was positive in 31(58.49%) patients. Bronchial brush and punch biopsy were positive in 15(60%) and 7(63.63%) patients respectively. CT/ USG guided biopsy yielded diagnosis in 32 out of 35 (94.23%) patients. Pleural fluid aspiration and pleural biopsy yielded diagnosis in 46.66% and 73.33% patients respectively.
Conclusion: Bronchoscopy is useful tool for diagnosis of centrally located lung cancer while CT/USG guided lung biopsy is superior for peripherally located lung cancer. Pleural fluid biopsy is useful for diagnosis where pleural fluid cytology is negative for malignancy.
Key Words; Lung cancer, Fibreoptic bronchoscopy, pleural biopsy.
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Corresponding Author
Dr. Radha Munje
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DOI: https://dx.doi.org/10.18535/jmscr/v5i9.49
