Abstract
A female, aged 65 years had splenomegaly and atypical lymphocytes in blood smear. Atypical cells had large round nuclei. Flow cytometric (FCM ) findings revealed positivity of atypical cells for CD19, CD103 and CD11c antigens. She was diagnosed as a case of hairy cell leukemia – variant (HCL-V) subtype. Satisfactory treatment protocol is not available for HCL-V. However, she was advised treatment with monoclonal anti CD 20 antibody (Rituximab 600 mg ivi weekly × 4 doses).
Keywords: Hairy cell leukemia – variant.
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Corresponding Author
Ashok Kumar Kapoor
RML Mehrotra Pathology Pvt Ltd, B-171, Nirala Nagar,
Lucknow-226020, Uttar Pradesh, INDIA
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v5i9.32
