Title: Prevalence and Clinical Course of Acute Kidney Injury (AKI) in Critically Ill Patients Admitted in Pediatric Intensive Care Unit- A Prospective Observational Study
Authors: Dr Manish Verma, Dr Sandeep Choudhary, Dr Vishnu Kumar Goyal, Dr Jai Prakash Soni
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.148
Abstract
Aims: To study the prevalence of acute kidney injury (AKI) in critically ill patients and to assess the outcome of critically ill patients with AKI.
Settings and Design: Single center prospective observational study was conducted over one year at Tertiary care Pediatric Intensive Care Unit (PICU) in Western Rajasthan, India.
Methods and Materials: 1467 patients fulfilled admission criteria, out of them 149 patients suffered with AKI on admission or later. AKI was categorized by AKIN staging. Associated comorbidities were identified and clinical course followed till discharge/expiry.
Statistical Analysis: Analysis of data was done by using SPSS version 15. Differences in distribution of categorical variables were assessed by chi square test.
Result: AKI found in 10.16% of total PICU admissions. These patients required higher percentage of inotropic (47.65%) and mechanical ventilatory support (40.27%) with longer PICU stay (6.96±4.18 days) and increase mortality in compare to patients without AKI. Septicemia (53.02%), shock (47.65%), perinatal asphyxia (14.09%) and gastroenteritis (11.41%) were leading comorbidities associated with AKI.
Conclusion: AKI is common in PICU patients and associated with a grave prognosis. So we need to early diagnosis and management of AKI in critically ill patients.
Keywords: AKI, PICU, mechanical ventilation, vaso-pressor.
