Clinical, Etiological and Prognostic Factors of Cerebral Venous Sinus Thrombosis in Kashmir-North India

Title: Clinical, Etiological and Prognostic Factors of Cerebral Venous Sinus Thrombosis in Kashmir-North India

Authors: Sheikh Nawaz Ahmad, Raouf Parvaiz Asmi, Gulzar Ahmad Bhat, Rayees Tarry, Tanveer Hassan, Mudasir Mushtaq

DOI: https://dx.doi.org/10.18535/jmscr/v5i4.100

Abstract

Background: Cerebral venous sinus thrombosis (CVST) has a variable clinical presentation making early diagnosis difficult. A number of prothrombotic states have been implicated in causation of CVST, but results are mixed.

Aims: The study was aimed to find out the clinical, etiological and prognostic factors of CVST in Kashmir-North India.

Materials and Methods: The study was carried out in a tertiary care hospital where all patients of CVST admitted between 1st August 2014 and 31^st July, 2016 were included in the study. The enrolled patients were studied for their demographic profile and a 2-5ml blood sample was collected from the subjects as well. Patients were followed up for minimum period of 6 months and outcome was assessed on the basis of morbidity and mortality.

Results: A total of 36 patients of CVST were included in the study. The mean age of the patients was 35.5years with highest representation (38.89%) among 31-40years age group. Headache was present in 94.4%. 30 patients (83.3%) were alive at the end of follow-up and 6 patients died (16.6%). Among various etiological factors purperium has a maximum representation (33.33%). Out of 32 female patients in the study group, 16 (44.44%) female patients had puerperium and 06 (16.66%) had oral contraceptive as a risk factor. Unconscious with purposive movements was observed in 27.78 % of the subjects. Out of 39 patients who survived, 31 cases (79.4%) had no disability symptoms, 5 patients had mild disability (13%) and 3 patients had moderate disability at six months of follow-up.

Conclusion: Purperium appears to be the main etiological factor and headache as the most common system for CVST in study population.

Keywords: Clinical; etiological; prognostic factors, Cerebral Venous Sinus Thrombosis; Kashmir.

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Abstract

Call For Paper Volume 12 Issue 10 November 2024

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Impact Factor SJIF 2024: 7.892

Crossref - DOI

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