Abstract
Follicular dendritic cells are localized in germinal centers of lymphoid follicles and play an integral role in regulation of the germinal center reaction and present antigens to B cells. A 22 year male patient presented with a well-defined mass around splenic flexure. On resection cut surface was smooth, fleshy and tan. On microscopy large pleomorphic cells with vesicular nuclei and prominent nucleoli intermingled with mature lymphocytes were present. Three mitotic figures /10HPF were noted. IHC was positive for Vimentin, CD21, CD23. Based on histological appearance and immunoprofile of the tumor, the diagnosis of Follicular dendritic cell sarcoma was made.
Key words: FDCS, IHC, CD21, CD23.
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Corresponding Author
Yamini Jindal
Dept of Pathology, Moti lal Nehru Medical College
Allahabad, Uttar Pradesh, 211001, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone No.- 91-7376923160
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.50
