BCR-ABL1 Fusion Gene Positive Chronic Myeloid Leukemia

Title: BCR-ABL1 Fusion Gene Positive Chronic Myeloid Leukemia - Chronic Phase in Childhood

Authors: Guddi Rani Singh, Rawi Agrawal, Bipin Kumar, Ajeet Kumar, Amit Kumar Sinha, Suryajit Kumar Singh

DOI: https://dx.doi.org/10.18535/jmscr/v5i4.10

Abstract

Philadelphia chromosome (Ph1)-positive Chronic Myelogenous Leukemia (CML) in a child below the age of 10 years is extremely rare. We have reported such a case in a 9 year old female child. Peripheral blood smear and bone marrow revealed features of CML and karyotypic study showed(Ph1) positivity. Biologic behaviour and prognosis are similar to that of adult-type of CML. we are reporting this case because of its extremely uncommon incidence.

Key Words: Chronic myeloid leukemia (CML), adult type CML, childhood leukemia.

References

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