Title: Cutaneous Metastases of Internal Malignancies: A Retrospective Study from a Tertiary Care Centre in Sub-Himalayan Region
Authors: Dr Mudita Gupta, Dr G K Verma, Dr GR Tegta, Dr Shikha Sharma
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.04
Abstract
Background: Cutaneous metastases (CM) are perceived as a sign of advanced disease and are regarded as a grave prognostic indicator.
Materials and Methods: Cases of metastatic tumor deposits in the skin from internal malignant malignancies and lymphomatoid malignancies were recorded from 2014-2016 from the old records of our college
Results: Fourteen cases of cutaneous metastases were recorded: 7 males and 7 females. The age range was 40 to 73 years, with a mean of 56.2 years. Firm multiple nodules were the most relevant clinical presentation in 42.85% of the cases. In 4 cases (28.5 %), cutaneous metastasis was the presenting sign and in rest 10 patients (71.4%) the cutaneous lesions appeared after treatment of malignancies. Most common primary malignancy metastasizing to skin was breast The most common site of metastasis was abdomen in 42.8 % cases, followed by lower back, extremities were rarely involved. Distant metastasis was seen in 35.7 % cases.
Conclusion: Cutaneous metastases are important to recognize because they may help in diagnosing an unknown carcinoma, recurrence of malignancy. Generally cutaneous metastases are poor prognostic signs.
Keywords: Cutaneous metastases, Renal cell carcinoma, Carcinoma breast.
