Abstract
Background: Peripheral lymphadenopathy is commonly due to infectious or benign disease, but it could be a feature of underlying malignancy. Fine needle aspiration cytology (FNAC) is a simple, rapid and cost effective method that can be used as reliable diagnostic modality.
Objective: The present study was done to evaluate etiological pattern of peripheral lymphadenopathies and distribution with the respect to the age, sex & site.
Material and Methods: The present study was conducted in the Department of Pathology, M.G.M. Medical College Indore, from October 2013 to September 2015. Total 795 cases were studied. Aspirations were done by using 20 ml syringe and 22/24 gauge needles. Smears were stained with Papanicolaou stain.
Results: Out of 795 cases, 396 were males and 399 were males with age range from 1 year to 80 years. Maximum number of cases 221 (27.8%) were in the age group of 21 to 30 years. Most common lesion was tuberculous lymphadenitis (36.9%) followed by reactive hyperplasia (26.4%), acute suppurative lymphadenitis (15.1%), metastatic carcinoma (14.8%), chronic granulomatous lesion (5.9%) and lymphoma (0.9%).
Conclusion: FNAC is very useful diagnostic modality for peripheral lymphadenopathies. It can distinguish inflammatory from malignant lesion so that unnecessary surgery can be avoided.
Keywords: Peripheral lymphadenopathy, Fine needle aspiration cytology, tuberculous lymphadenitis.
References
1. Pandit AA, Candes FP, Khubchandani SR. Fine needle aspiration cytology of lymph nodes. J Postgrad Med 1987;33:134-6.
2. Mohseni Sh, Shojaiefard A, Khorgami Z, Alinejad Sh, Ghorbani A, Ghafouri A. Peripheral Lymphadenopathy: Approach and Diagnostic Tools. Iran J Med Sci Supplement March 2014; Vol 39 No 2.
3. Gupta AK, Nayar M, Chandra M. Critical appraisal of fine needle aspiration cytology in tuberculosis. Acta cytol.1992;36:391-94
4. Kumar N , Gupta BB, Sharma B, Kaushal M, Rewari BB, Sundriyal D. Role of fine needle aspiration cytology in human immunodeficiency virus–associated lymphadenopathy: a cross-sectional study from northern India. Hong Kong Med J. 2015;21(1):39-44.
5. Wu M, Burstein DE. Fine needle aspiration. Cancer Invest 2004;22:620-8.
6. Keith VE, Harsharan SK, Jerald GZ. Fine needle aspiration biopsy of lymph nodes in the modern era: reactive lymphadenopa-thies. Pathol Case Rev 2007;12(1):27–35.
7. Gayathri MN et al. Pattern of lymphadenopathy in fine needle aspiration cytology: a retrospective study. Int J Res Med Sci. 2015 Jun;3(6):1416-1419.
8. Shah PC et al. Evaluation of peripheral lymphadenopathy by fine needle aspiration cytology: a one year study at tertiary centre Int J Res Med Sci. 2016 Jan;4(1):120-125.
9. Shilpa G, Nataraju G. Pattern of Lymph Node Diseases in a Tertiary Level Referral Center: a cytological study of 943 cases. International Journal of Biological and Medical Research. 2013;4(3):3448-52.
10. Patel MM, Italiya SL, Patel RD, Dudhat RB, Kaptan KR, Baldwa VM. Role of Fine Needle Aspiration Cytology to Analyze Various Causes of Lymphadenopathy. Natl J Community Med. 2013;4(3):489-92.
11. Shrivastav et al. Evaluation of peripheral lymphadenopathy by fine needle aspiration cytology: A three year study at tertiary center. Journal of Dr. NTR University of Health Sciences 2014;3(2) 86-91.
12. Khajuria R, Goswami KC, Singh K, Dubey VK. Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu. JK Sci 2006;8:157-9.
13. Wahid FI, Rehman H, Khan Q, Shahabi IK. Diagnostic value of fine needle aspiration cytology in diagnosis of non-thyroidal neck mass. JPMI. 2010;24 (4):289-94.
14. Mohanty R, Wilkinson A. Utility of Fine Needle Aspiration Cytology of Lymph nodes. IOSR Journal of Dental and Medical Sciences. 2013;8(5):13-8.
15. Hiremath SS, Murgud S. Cytohistopathological evaluation of the cervical lymph nodes by fine needle aspiration cytology. Journal of Cranio-Maxillary Diseases. 2014;3(2):101-5.
16. Alam K, Khan AH, Siddiqui FA, Jain A, Haider N. Fine Needle Aspiration Cytology (FNAC), a handy tool for metastatic lymphadenopathy. The Internet Journal of Pathology 2010;10. Available from: http://www.ispub.com/journal/the_internet_journal_of_pathology.
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.198
