Clinicopathological Profile of Metastatic Cervical Lymph Nodes- A Descriptive Study in a Tertiary Care Centre

Title: Clinicopathological Profile of Metastatic Cervical Lymph Nodes- A Descriptive Study in a Tertiary Care Centre

Authors: Dr Praveen N., Dr. Swathilal. S. A., Dr Lakshmanan. P. P., Dr Deeps. C. K.

DOI: https://dx.doi.org/10.18535/jmscr/v5i3.137

Abstract

The single most important factor determining the survival of patients with head and neck malignancy is the presence or absence of metastatic disease in the neck. clinicopathological profile of metastatic lymph nodes were conducted in the department of surgery, Medical College, Kozhikkode for a three years. Thirty nine cases of head and neck malignancy having either clinically evident cervical metastasis or those with a high chance of occult metastasis were selected. Twenty six of 39(66.7%) were male with male to female ratio 2.1 The mean age was 58.7(10.7) years. Most of the patients in this study belonged to 61-70 year group. The most common site of the primary lesion was at the anterior tongue(41%).Twenty one (53.8%) patients was at stage II, followed by 11(28.2%) patients in the stage III. The most common symptom was ulcer of the oral cavity(60%) followed by neck swelling in 15%. Cervical nodes were pathologically positive for metastasis in twenty one of the thirty nine cases (53.8%) of these seven were unilateral and four were bilateral. The commonest presenting feature was ulcer in the mouth followed by neck swelling,pain in the mouth, difficulty in swallowing, change in voice and ankyloglossia. The present study revealed most of the lesion were of ulcerative type.

References

1. Martin H. Cancer of the head and neck. Journal of the American Medical Association 1948; 137(16): 1366-76.

2. Garg M, Beitler JJ. Controversies in management of the neck in head and neck cancer. Current treatment options in oncology 2004; 5(1): 35-40.

3. Kowalski LP, Sanabria A. Elective neck dissection in oral carcinoma: a critical review of the evidence. Acta Otorhinolary-ngologica Italica 2007; 27(3): 113-7.

4. Sakaguchi T, Yamashita Y, Katahira K, et al. Differential diagnosis of small round cervical lymph nodes: comparison of power Doppler US with contrast-enhanced CT and pathologic results. Radiation medicine 2001; 19(3): 119-25.

5. Anand N, Chaudhary N, Mittal MK, Prasad R. Comparison of the efficacy of clinical examination, ultrasound neck and computed tomography in detection and staging of cervical lymph node metastasis in head and neck cancers. Indian Journal of Otolaryngology and Head & Neck Surgery 2007; 59(1): 19-23.

6. Kallalli B, Rawson K, Kumari V, Patil S, Singh A, Sulaga S. Comparison between clinical examination, ultrasonography, and computed tomography in assessment of cervical lymph node metastasis in oral squamous cell carcinoma. Journal of Indian Academy of Oral Medicine and Radiology 2016; 28(4): 364-9.

7. Dralle H, Musholt TJ, Schabram J, et al. German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors. Langenbeck's Archives of Surgery 2013; 398(3): 347-75.

8. Carlson ER, Cheung A, Smith B, Pfohl C. Neck dissections for oral/head and neck cancer: 1906–2006. Journal of Oral and Maxillofacial Surgery 2006; 64(1): 4-11.

9. Ferlito A, Rinaldo A, Silver CE, et al. Elective and therapeutic selective neck dissection. Oral oncology 2006; 42(1): 13-24.

10. Samant S, Robbins KT. Evolution of neck dissection for improved functional outcome. World journal of surgery 2003; 27(7): 805-10.

11. Kerr AG. Scott-Brown's Otolaryngology No-4Rhinilogy: London: Butter worth, 1987; 1987.

12. Shah JP, Candela FC, Poddar AK. The patterns of cervical lymph node metastases from squamous carcinoma of the oral cavity. Cancer 1990; 66(1): 109-13.

13. Carvalho AL, Singh B, Spiro RH, Kowalski LP, Shah JP. Cancer of the oral cavity: a comparison between institutions in a developing and a developed nation. Head & neck 2004; 26(1): 31-8.

14. Sankaranarayanan R, Nair MK, Mathew B, Balaram P, Sebastian P, Dutt SC. Recent results of oral cancer research in Kerala, India. Head & neck 1992; 14(2): 107-12.

15. Hamner J. Aetiology and epidemiology of oral cancer. Cancer and the Oral Cavity 1986: 17-30.

16. Kuriakose M, Sankaranarayanan M, Nair MK, et al. Comparison of oral squamous cell carcinoma in younger and older patients in India. European Journal of Cancer Part B: Oral Oncology 1992; 28(2): 113-20.

17. Bruun JP. Time lapse by diagnosis of oral cancer. Oral surgery, oral medicine, oral pathology 1976; 42(2): 139-49.

18. Silverman S, Griffith M. Smoking characteristics of patients with oral carcinoma and the risk for second oral primary carcinoma. The Journal of the American Dental Association 1972; 85(3): 637-40.

19. Smith EM. An analysis of cohort mortality from tongue cancer in Japan, England and Wales and the United States. International journal of epidemiology 1982; 11(4): 329-35.

20. Reddy CR. Carcinoma of hard palate in India in relation to reverse smoking of chuttas. Journal of the National Cancer Institute 1974; 53(3): 615-9.

21. Droulias C, Whitehurst J. The lymphatics of the tongue in relation to cancer. The American surgeon 1976; 42(9): 670.

22. Gleeson M. Scott-Brown's Otorhinolary-ngology: Head and Neck Surgery 7Ed: 3 volume set: CRC Press; 2008.

Dr Praveen N.

Associate Professor of Plastic Surgery

Medical College, Thiruvananthapuram

Abstract

References

Corresponding Author

Call For Paper Volume 12 Issue 10 November 2024

JMSCR Menu

Impact Factor SJIF 2024: 7.892

Crossref - DOI

Editorial Policy

Frequency of Publication

Submission of Articles

Search

Abstract

Call For Paper Volume 12 Issue 10 November 2024

JMSCR Menu

Impact Factor SJIF 2024: 7.892

Crossref - DOI

Editorial Policy

Frequency of Publication

Submission of Articles