Title: Study on Mean Platelet Volume in Type 2 Diabetes Mellitus Patients vs Non Diabetic Patients
Authors: Madhavan K, Priyadarshini V, Sivaprakash V, Bharath Kumaran M
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.51
Abstract
Increased prevalence of vascular disease is seen in patients with Diabetes Mellitus (DM). Enhanced reactivity of platelets in patients with diabetes has been postulated to play a role in the microvascular and macrovascular complications of diabetes. MPV is being evaluated as a marker of increased platelet activation. This is a cross-sectional prospective study to evaluate MPV in patients with type 2 diabetes versus non-diabetic patients and to investigate the potential association between MPV and chronic diabetic complications. Our study revealed that MPV is increased in Diabetes mellitus (DM) and that platelets become more reactive and aggregable. The increased platelet size may be a risk factor for atherosclerosis associated with DM and its vascular complications. Hence, MPV would be a useful prognostic marker of cardio-vascular complications in Diabetes mellitus (DM).
Keywords: cardiovascular complications , diabetes mellitus, HbA1c, mean platelet volume.
