Siddha system is a treasure house of a secret science embodying several medicines for curing several diseases. But this is a time to standardise siddha drugs for world acceptance for the safety concerned. This paper deals with the physico-chemical properties, and Instrumental analysis of Gandhaga parpam for part of standardisation as per AYUSH Guidelines. The physico-chemical analysis the drug shows the quality of the drug. FTIR Interprets the molecular structure of the sample.SEM analysis showed the size of the drug particle, is in Nanometre which denotes that the trial drug could have potent drug delivery.XRF analysis disclosed the percentage of elements presence in the drug. Based on the results the drug Gandhaga parpam was standardised as part. Further advanced study will need to full fill the standardisation. This paper will help the physicians and researchers to do the needful in the world health society.

Keywords: Gandhaga parpam, Siddha, physico-chemical analysis, AYUSH Guidelines, Instrumental analysis.