Abstract
Intrathecal (IT) neostigmine has been used as an adjunct to spinal anaesthesia. The purpose of this study was to determine whether a combination of low-dose neostigmine IT would enhance analgesia of xylocaine IT, in patients undergoing lower abdominal and lower limb surgeries under spinal anesthesia. Study was done on 45 patients, who were divided into 6 groups these groups were given neostigmine in various concentrations (.25mg,.5mg &.75mg) along with 5% xylocaine (heavy) IT with control group receiving only IT xylocaine.
Hence, Low dose neostigmine (0.25 mg) when added to xylocaine IT enhances duration of analgesia without affecting significantly cardiovascular status, duration of motor paralysis and adverse effects. Thus more and more use of low dose neostigmine as an adjunct to xylocaine (heavy) I.T. is being recommended.
Key words: Xylocaine, Neostigmine, Spinal Anaesthesia.
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Corresponding Author
Dr Sapna Singh
Assistant Professor, Department of Anesthesia
Jaipur National University Institute of Medical Science & Research Centre, Jagatpura, Jaipur – 302017
DOI: http://dx.doi.org/10.18535/jmscr/v4i4.33
