Abstract

Background: Osteoarthritis (OA) is one of the most distressing chronic condition which affecting people specially in elder around the world. Recently PRP has been used for the treatment of knee osteoarthritis globally. Osteoarthritis (OA) is a major reason of knee disability involving cartilage damage related to an inadequate healing response in the inflammatory process. Current non-surgical treatment modalities include physiotherapy, analgesia, non-steroidal anti-inflammatory drugs, and intra-articular injections, such as hyaluronic acid (HA), corticosteroids, or Ozone, with the purpose of reducing symptoms and improving joint function. Now a day’s PRP has been used for the treatment of knee osteoarthritis worldwide.

Objective: Our main goal is to assess the effectiveness of PRP therapy that reduces pain and leads to a more effective and lasting functional recovery with local anesthetic in intra-articular steroid failure elderly patients.

Method: This cross-sectional comparative study was carried out from January 2018 to July 2018at the Department of Transfusion Medicine, Bashundhara Ad-din medical college and hospital, South Keranigonj. During the study 50 purposive voluntary, non-remunerated altruistic patients were studied where Male was 28 and Female was 22. All patient’s full history, general examination and complete knee joint examination was categorized and data of the patients were entered on the Statistical Package for Social Science (SPSS).

Results: This study result shows that, in advanced aged patients there was improvement of pain after two doses of Platelet Riched Plasma (PRP) where they showed no significant improvement after two doses of intra articular steroid injection earlier.

Conclusion: From our result, we can conclude that it was found that intra-articular injection of PRP is an effective and safe method for treatment of knee OA for elderly patients with no complication

Keywords: Osteoarthritis, PRP therapy, Cartilage.