Abstract
Aim of the Study
To analyze the pattern of clinical presentation and diagnostic investigations in Hepatoblastoma, and to discuss the results of Hepatic resection with neo-adjuvant and/or adjuvant chemotherapy
Method of Study
Retrospective analysis of all the hospital data of 10 children who underwent Hepatic resection for Hepatoblastoma during the period of May 2004 to May 2006 was studied, as a part of a long term study of all cases of Hepatic resection done during the period of 2004 – 2018 at a single institution, which has been divided into 3 phases : 2004-06, 2007-10 and 2011-18. The results during the period of 2004-2006 is being presented here as a pilot study.
Primary Hepatic resection for hepatoblastoma and surgeries done after neo-adjuvant chemotherapy are included in the analysis.
References
- von Schweinitz D, Hecker H, Harms D et al. Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma—A report from the German Cooperative Pediatric Liver Tumor Study HB-89. J Pediatr Surg 1995;30:845-852.
- Brown J, Perilongo G, Shafford E et al. Pretreatment prognostic factors for children with hepatoblastoma—results from the International Society of Paediatric Oncology (SIOP) Study SIOPEL 1. Eur J Cancer 2000;36:1418-1425.
- Jabra AA, Fishman EK, Taylor G. Hepatic masses in infants and children: CT evaluation. Am J Roentgenol 1992;158:143-149.
- Pierro A, Langevin AM, Filler RM et al. Preoperative chemotherapy in "unresectable" hepatoblastoma. J Pediatr Surg 1989;24:24-28
- Gazelle GS, Haaga JR. Hepatic neoplasms: surgically relevant segmental anatomy and imaging techniques. Am J Roentgenol 1992;158:1015-1018
- Stringer MD, Hennayake S, Howard ER et al. Improved outcome for children with hepatoblastoma. Br J Surg 1995;82:386-391.
- Exelby PR, Filler RM, Grosfeld JL. Liver tumors in children in the particular reference to hepatoblastoma and hepatocellular carcinoma: American Academy of Pediatrics Surgical Section Survey-1974. J Pediatr Surg 1975;10:329-337.
- Lee CL, Ko KC. Survival and distribution pattern of childhood liver cancer in Taiwan. Eur J Cancer 1998;34:2064-2067.
- Saxena R, Leake JL, Shafford EA et al. Chemotherapy effects on hepatoblastoma. A histological study. Am J Surg Pathol 1993;17:1266-1271.
- Stocker JT. An approach to handling pediatric liver tumors. Am J Clin Pathol 1998;109:S67-S72.
- Seo T, Ando H, Watanabe Y et al. Treatment of hepatoblastoma: less extensive hepatectomy after effective preoperative chemotherapy with cisplatin and Adriamycin. Surgery 1998;123:407-414.
- Bleacher JC, Newman KD. Hepatoblastoma. In: Andrassy RJ, ed. Pediatric Surgical Oncology. Philadelphia: W. B. Saunders, 1997:213-220.
Corresponding Author
Dr Sunil S Menon
12 Vasanth Vihar Gardens Kumarapuram, Thiruvananthapuram, Kerala, India, Pin 695011
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone 9446127448, Phone 04712528390
DOI: https://dx.doi.org/10.18535/jmscr/v6i8.161
