Abstract
Background: Urine examination also referred to as liquid renal biopsy has provided valuable clinical information about the functional status of the kidney. These results can be relied for a number of applications, including screening for diagnosis of asymptomatic disease, monitoring and following the course of a disease. Deplorably, because of the routine nature of this test, pathologists often spend comparable time examining both normal and abnormal urine specimens in an unsystematic fashion.
Methodology: Dipstick and microscopy urinalyses were carried out on 100 consecutive urine samples of patients and the results were statistically analyzed.
Results: Age of patients ranged from 1 month to 80 years. Male patients were in a higher number than females in most of the age groups. Dipstick showed sensitivity of 82%, 76% and 87% and specificity of 71%, 92% and 89% for leukocytes, nitrite and blood respectively.
Conclusion: The urinalysis by dipstick method should be followed by the microscopy for more accurate and valid results.
Keywords: Urinalysis, urine reagent strips, microscopy.
References
- Prabahar MR, Chandrasekaran V, Soundararajan P. Epidemic of Chronic Kidney Disease in India - What Can Be Done? Saudi J Kidney Dis Transpl 2008;19:847-53.
- Prigent A. Monitoring renal function and limitations of renal function tests. Semin Nucl Med. 2008 Jan;38(1):32-46.
- Marcussen N, Schumann J, Campbell R, Kjellstrand C. Cytodiagnostic urinalysis is very useful in the differential diagnosis of acute renal failure and can predict the severity. Ren Fail. 1995;17:721-9.
- Obroniecka I, Rojewska J, Wancowicz Z. The value of urine sediment cytomorp-hology in the ambulatory differential diagnosis of hematuria. Pol Merkur Lekarski. 1998 Nov;5(29):285-7.
- Morrison MC, Lum GDipstick Testing of Urine—Can It Replace Urine Microscopy? Am J Clin Pathol 1986; 85: 590-594.
- World Health Organization. Manual of basic techniques for a health laboratory (2nd Ed). Geneva; World Health Organization, 2003.
- Valenstein PN, Koepke JA: Unnecessary microscopy in routine urinalysis. Am J Clin Pathol 1984; 82:444-448.
- Kiechle FL, Karcher RE, Epstein E: Routine microscopic examination of the urine sediment revisited. Arch Pathol Lab Med 1984; 108:855-856.
- Smalley DL, Bryan JA: Comparative evaluation of biochemical and microscopic urinalysis. Am J Med Technol 1983; 49:237-239.
- Christenson RH, Tucker JA, Allen E: Results of dipstick tests, visual inspection, microscopic examination of urine sediment, and microbiological cultures of urine compared for simplifying urinalysis. ClinChem 1985;31:448-450.
- Nanji AA, Adam W, Campbell DJ: Routine microscopic examination of the urine sediment—Should we continue? Arch Pathol Lab Med 1984; 108:399-400.
- Resnick M: Simplifying urinalysis. Clin Chem 1985; 31:450-451.
- Szwed JJ, Schaust C: The importance of microscopic examination of the urinary sediment. Am J Med Technol 1982; 48:141-143.
- Tetrault GA. Automated reagent strip urinalysis: utility in reducing work load of urine microscopy and culture. Lab Med. 1994;25:162-167.
- Bartlett RC, Zern DA, Ratkiewicz I, Tetreault JZ. Screening for urinary tract infection with the Yellow IRIS. Lab Med. 1992;599-602.
- Shaw ST Jr, Poon SY, Wong ET. “Routine urinalysis”: is the dipstick enough? JAMA.1985;253: 1596-1600.
- Bataille A, Wetzstein M, Hertig A, Vimont S, Rondeau E, Galichon P. Evidence of dipstick superiority over urine microscopy analysis for detection of hematuria. BMC Res Notes 2016;9:435.
- Anigilaje EA, Adedoyin OT. Correlation between dipstick urinalysis and urine sediment microscopy in detecting haematuria among children with sickle cell anaemia in steady state in Ilorin, Nigeria. Pan Afr Med J. 2013; 15:135.
- Wenk RE, Dutta D, Rudert K, et al. Sediment microscopy, nitriteuria and leukocyte esteraseuria as predictors of significant bacteriuria. J Clin Lab Automation 1982; 2: 117-21.
- Wilkins EGL, Ratcliffe JG, Roberts C. Leucocyte-esterasenitrite screening method for pyuria and bacteriuria. J Clin Pathol 1985; 38: 1342-5.
Corresponding Author
Dr Meghana P
Department of Pathology, Mysore Medical College and Research Institute,
Mysuru, Karnataka, India
Phone number – 9591402851, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.159
