Gastroprotective Effects of Gloriosa Superba Tubers against HCL/Ethanol Induced Gastric Mucosal Injury in Rats

Title: Gastroprotective Effects of Gloriosa Superba Tubers against HCL/Ethanol Induced Gastric Mucosal Injury in Rats

Auhors: Siddhi Ashokkumar Mehta Falguni, Mrs. Rachana D. Sarawade, Ayyub Shaikh, Vishakha Trivedi, Freny Menezes

DOI: http://dx.doi.org/10.18535/jmscr/v3i8.43

DIDS : 08.2015-XXXXXXX

Abstract

References

Corresponding Author

Abstract

The purpose of this study was to evaluate gastroprotective activity of Gloriosa superba tuber extract (GSTE) on HCL/Ethanol induced gastric ulcers. Gloriosa superba plant is used for treatment of various diseases. Disease control group exhibited severe mucosal injury as compared to standard group (Omeprazole) and test group (GSTE) which showed protection towards gastric mucosal injury. Gastric wall mucus was significantly replenished by the pre treatment of test group and standard group which was reduced by HCL/Ethanol. Also antioxidants enzymes (SOD and LPO) were also brought back to normal level up to certain extent by test drug and Omeprazole.

Keywords: Gastroprotective, Gloriosa superba, SOD, LPO.

References

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