Abstract
Objective: To compare the efficacy of Silodosin and Tamsulosin as a medical expulsive therapy given for the conservative management of distal ureteric calculus in terms of Stone Clearance Rate.
Patient and Methods: A Prospective Observational Analytical Study was conducted on 120 cases between 18 years and 75 years with Unilateral distal ureteral single calculus (Distal to Iliac vessel crossing) and size less than or equal to 1 cm. The cases of this study were divided into two groups: Group A receiving Silodosin 8 mg tablet once daily and Group B receiving Tamsulosin 0.4mg capsule once daily. These patients were investigated with Serum Creatinine, X-ray KUB and USG KUB during the initial diagnosis. Each group received treatment for a period maximally 1 month. During this period the patient were evaluated for passage of calculus 2 weekly by Clinical history and by USG & NCCT (only incase USG was inconclusive).
Results: There was a significantly higher stone clearance rate of 81.67% in Group A vs 63.33% in Group B. Group A also showed a significant advantage for stone expulsion time.
Conclusions: Our data showed that silodosin is more effective than tamsulosin in the management of lower ureteric calculus for stone clearance rates and stone expulsion times.
Keywords: Silodosin; tamsulosin; distal ureteric stones, stone clearance.
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Corresponding Author
Dr Nipun Bansal
Urology Resident, Department of Urology, Father Muller Medical College, Mangalore, Karnataka, India
DOI: https://dx.doi.org/10.18535/jmscr/v10i11.16
