Background: Stroke is one of the most frequent causes of death and disability worldwide with a significant clinical and socioeconomic impact. The objectives were to know whether there is a role for dyslipidemia in the occurrence of ischemic strokeand if there is any difference in the various lipid parameters of the case and control groups.

Aims and Objective: To determine the role of lipid parameters on the occurrence of ischemic stroke and its comparison with age and sex-matched controls.

Material and Methods: A case-control study was done and a total of 48 patients with acute ischemic stroke were chosen. An equal 48 controls were included in this study for the comparison of outcome. A serum sample after 8 hours of overnight fasting was taken on the next day of admission for both groups of patients. Total serum cholesterol, triglycerides, LDL-cholesterol, and HDL-cholesterol were determined, using the enzymatic colorimetric method.

Results: In 48 ischaemic stroke patients, raised serum total cholesterol was seen in 11, triglyceride in 15 and LDL-cholesterol in 16 patients. On the other hand, raised serum total cholesterol observed in 10, triglyceride in 12, LDL-cholesterol in 12 age and sex matched 48 control subjects. Serum HDL-cholesterol was below the normal reference in 09 cases and 04 controls subjects. On comparison, no statistical significance was found on comparing abnormal values of both groups for total cholesterol, triglycerides, LDL-C and HDL-C. Also after comparing mean values for different lipid parameters no significant association observed in our study.

Conclusion: We found that lipid profile values are not associated with an increased risk of ischaemic stroke.

Keywords: Diabetes, Dyslipidemia, Infarct, Ischemia.

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Gaurav Gupta