Title: Post contrast T2 -FLAIR sequence - can it be a predictor of disease activity in tuberculomas of brain – findings from a preliminary study

Author: Dr Bindu R Kumar

 DOI: https://dx.doi.org/10.18535/jmscr/v8i6.111

Abstract

Aim: To assess the use of pre and post contrast T2 FLAIR images in brain scans in CNS tuberculomas as a predictor of disease activity.

Materials and Methods: T2 FLAIR pre and post contrast images and T1w post contrast images of clinically proven cases of tuberculomas in brain in various stages of antituberculous treatment were taken. The images were reviewed to particularly study the intensity and enhancement of the lesions.

Result: There was a clear difference in the enhancement of the rim of the tuberculoma in patients in different stages of antituberculosis treatment on T2 FLAIR images.

Conclusion: The results of the study are from a small sample. Our study was based on only six patients and hence is only a preliminary study. A study with a larger sample size is needed.

Keywords: Tuberculoma, T2 FLAIR, pre and post contrast images.

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