Background: Amniotic fluid is the protective liquid contained by the amniotic sac of a growing fetus. Amniotic fluid index (AFI) is a quantitative estimation of amniotic fluid volume in centimeter. The amount of amniotic fluid volume varies according to age of gestation. In the third trimester the decrease amount of amniotic fluid may cause IUGR, IUD, pre-term birth, foetal distress, cord compression, increase incidence of caesarean delivery etc which leads to increase operative interference and increase neonatal complications.

Objectives: To compare the efficacy of different amino acid supplement during third trimester in two different routes and also to compare the efficacy of both route in improvement of AFI in third trimester.

Method: This study was conducted on 132 pregnant women’s with gestational age >32 weeks. Patients were divided in two groups of 66 patients each group. One group was prescribed with intravenous amino acid infusion, and the other group was prescribed with oral amino acid supplementation for two consecutive weeks. Data collected on day one was compared with the data on 21st day of the treatment.

Result: The maternal hemodynamic status were unchanged for both groups. There were statistically significant difference in increase in maternal weight, AG, SFH, AFI, EFW in two groups.

Conclusion: In this study Intravenous amino acid infusion cause a notable increase in SFH, AG, AFI, EFW than oral amino acid supplementation.

Keywords: amniotic fluid, amino acid, abdominal girth, Estimated fetal weight.

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Lieutenant Colonel Dr. Md Fakhrul Alam

BSP, MPH, Commanding Officer, 11 Field Ambulance, Savar Cantonment, Bangladesh