Epidermodysplasia verruciformis (EV) is a rare disorder that is usually transmitted in an autosomal recessive manner, caused by human papillomavirus. It has tendency for malignant transformation, especially squamous cell carcinoma. These patients show a defect in cell-mediated immunity specific toward the causative HPVs that lead to lifelong disease. The defect is usually inherited as autosomal recessive trait and presents clinically with plane warts, pityriasis versicolor like lesions and reddish verrucous plaques. Here we present a case of 15 year boy with complaints of asymptomatic hypopigmented macular lesions and flat wart-like lesions over the face, neck, hands and forearms. Histopathology was suggestive of EV. He was given oral zinc, sunscreen and advised regular follow up.

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Ravinder Singh

Medical Officer Dermatology Dr RKGMC Hamirpur HP