Background: Orthopaedic implant infections are a common problem in all major orthopaedic units. Established implant infections can be evaluated with clinical and biochemical parameters.

CRP C-Reactive protein is an acute phase reactant. Normal value is 0-5 mg/Litre. Values above 10 mg / Litre are suggestive of definite implant infection.

Reduction intitrecorrelates with control of infection.

This study aims to study the correlation between implant infections and CRP levels in a government hospital.

Materials and Methods: This is a retrospective study of fifty patients who were admitted with various types of orthopaedic implant infections. This include Hip and knee joint arthroplasties, DCP, plates, intramedullary nails.

Results: All implant infections had CRP values above 20mg/L response to antibiotic suppression of infection reduced CRP to values below 10 mg/L.

Conclusion: CRP is a good marker of implant related infection both for diagnosis and monitoring the results of antibiotic treatment.

1. E. Antoci V-Analysis   of ESR,   CRP   in   diagnosing periprosthetic infectious prior to revision arthroplasty-2019.
2. K.E. Fernandez, steekleberg-C.R.P & ESR in orthopaedic implant infection 2015 (Pubmed).
3. Greidanus N V Masri B A etal use of ESR, CRP level to diagnosis infection before revision total knee arthroplasty 2007 (Pubmed).
4. Costa CR, Johnzon, Nazim. Efficacy of CRP level in determining periprosthetic Hip infections 2013 (Pubmed).
5. Johnson AJ, Zyniel M.G. Stron. A, serologic marker can lead to False negative Diagnosis of periprosthetic infections 2012 (Pubmed).
6. E. Gauvin. F. Amre DK CRP and Serum procalcitonin levels as markers for orthopaedic infections 2004(Pubmed).

Dr Sabarisree. M

Additional Professor in Orthopaedics, Government Medical College, Trivandrum