Title: Fertility preserving surgery for ovarian cancer in young patients
Authors: Dr Sai Sudha Alaparthi, Dr Kaushik Hari, Dr Madhavi Polu
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.46
Abstract
Ovarian cancer is considered to be one of the most lethal gynaecological malignancies. It is estimated that 10% of ovarian cancer cases will be diagnosed in women of reproductive age[1] and > 80% would be in advanced stage. Conservative treatment can be carried out for stage 1 to preserve fertility. However, accurate staging prior to surgery is difficult and some of these may require chemotherapy after fertility preserving surgery which affects ovarian reserve and there may be lot of after effects of chemotherapy on conception.
References
- Ditto A, Bogani G, Martinelli F, Raspagliesi F. Fertility-sparing surgery in high risk ovarian cancer. J Gynecol Oncol 2015;26:350-1.
- Fakhr I, Abd-allah M, Ramzy S, Mohamed AM, Saber A. Outcome of fertility preserving surgery in early stage ovarian cancer. J Egypt Natl Canc Inst 2013;25:219-22.
- Mangili G, Sigismondi C, Gadducci A, Cormio G, Scollo P, Tateo S, et al. Outcome and risk factors for recurrence in malignant ovarian germ cell tumours: A MITO-9 retrospective study. Int J Gynecol cancer 2011;21:1414-21.
- Colombo N, Guthrie D, Chiari S, Parmar M, Qian W, Swart AM, et al. International collaborative ovarian neoplasm trial 1: A randomised trial of adjuvant chemotherapy in women with early stage ovarian cancer. J Natl Cancer Inst 2003;95:125-32.
- Deodhar KK, Suryawanshi P, Shah M, Rekhi B, Chinoy RF. Immature teratoma of the ovary: A clinicopathological study of 28 cases. Indian J Pathol Microbiol 2011;54:730-35.
- Genes M, Neis F, Kramer B, Walter C, Brucker S, Von Wolff M, et al. Possibilities of fertility preservation in young patients with ovarian cancer. Anticancer Res2014;34:3851-4.