Title: Cartap Hydrochloride Poisoning - A Case Report
Authors: Prof Dr M. Senthilvelan, Dr Nageswaran. B, Prof Dr K. Baburaj, Dr A. Elaiyaraja
DOI: https://dx.doi.org/10.18535/jmscr/v7i10.116
Abstract
Cartap hydrochloride has been classified as a moderately hazardous insecticide by WHO. It is a nereistoxin analogue and poisoning with cartap is rarely reported in India. It promotes neuromuscular weakness resulting in respiratory failure. We report a 35 year old male who consumed 4% Cartap hydrochloride with alcohol and presented with respiratory failure.
Keywords: cartap hydrochloride, nereistoxin, respiratory failure.
References
- Liao JW, Kang JJ, Jeng CR, Chang SK, Kuo MJ, Wang SC, Liu RS, Pang VF. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology 2006; 219:73-84.
- Liao JW, Kang JJ, Liu SH, Jeng CR, Cheng YW, Hu CM, et al. Effects of cartap on isolated mouse phrenic nerve diaphragm and its related mechanism. Toxicol Sci 2000; 55: 453-9.
- Kumar ASP, Amalnath D, Dutta TK. Cartap poisoning: A rare case report. Indian J Crit Care Med 2011; 15:4.
- Kiyota K, Honma M, Shigeta M, Miyake Y, Sakamoto T, Aruga T, et al. Cartap intoxication – pharmacokinetic analysis. Jpn J Toxicol 1994; 7: 263-70.
- Cao BJ, Chen ZK, Chi ZQ. [Antidotal effects of sulfhydryl compounds on acute poisonings by sodium ammonium dimethyl-2-(propane-1, 3- dithiosulfate) monohydrate, nereistoxin and cartap]. Zhongguo Yao Li Xue Bao1990;11:180-4.
- Nagawa Y, Saji Y, Chiba S, Yui T. Neuromuscular blocking actions of nereistoxin and its derivatives and antagonism by sulfhydryl compounds. Jpn J Pharmacol 1971; 21:185-97.