Introduction: The Six Sigma plan measures the degree to which any process deviates from its goal. Six-sigma is a metric that quantifies the performance of processes as a rate of Defects-Per-Million Opportunities, (DPM, or DPMO). Sigma works on a quality principle of DMAIC which stands for Define, Measure, Analyse, Improve and Control.

Aims and Objectives: To evaluate our laboratory performance from Jan 2019 to June 2019 by estimating six-sigma.

Methodology: We evaluated sigma metric for 35 parameters run in our auto analyzers from Jan 2019 to June 2019 (6 months).Coefficient of variation which represents lab precision and BIAS which represents accuracy is calculated by using standard formulas. Later average six sigma was calculated from Jan 2019 to June 2019. Average Total error also was calculated for 6 months. To know about the goals for improvement in our laboratory after estimating six sigma we calculated quality goal index.

Results and Discussion:  Out of 35 parameters, we observed > 3 sigma metrics for 19 parameters of all levels. Parameters (T3, T4, TSH, Troponin I) and Gem Premier Instrument (pO2, pCO2) failed to show > 3 six sigma. The QGI showed that the problem lied with inaccuracy with these parameters. Sigma ≥6 is practically impossible to achieve. Total Protein and albumin has failed to achieve > 3 sigma metrics and imprecision problem lied with these parameters. Highest sigma metric was observed in pH, triglyceride, and lipase.

Conclusion: Our laboratory has performed considerably well after assessing through the sigma metric. Application of six sigma in laboratory can be a considerable indicator for quality and reducing number of IQC runs which can be cost effective. The drawback of not achieving standard world class six sigma all the time is still existing in healthcare. However quality reports with cost effectiveness should always be a dictum as a health care professional.

Keywords: Six Sigma, Coefficient of Variation, Total Allowable Error, Quality Goal Index.

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Dr Kavita P Rasalkar

Department of Biochemistry, PES Institute of Medical Science and Research, Kuppam