Title: An Overview of Cervical Cytology and Its Clinical Correlation Conducted in Gajraraja Medical College, Gwalior
Authors: Dr Shikha Asrani, Dr V. Joshi
DOI: https://dx.doi.org/10.18535/jmscr/v7i9.122
Abstract
Objectives: To evaluate all previously conducted pap smears examined at a teaching tertiary hospital during a one year period and its clinical correlation.
Introduction: In India cervical cancer is the leading cause of morbidity and mortality. Cancer of cervix is preventable and can be diagnosed at the pre-malignant pre-invasive stage with adequate and repetitive screening by cervical cytology.
Material and Methods: This is a retrospective study conducted in Department of Obstetrics and Gynaecology of GRMC, Gwalior from Jan 2018 to Dec 2018. Pap’s Smear were taken using Ayres Spatula from patients aged 20-70 years presenting with different gynaecological complaints in Gynaecology OPD as a routine screening test. A total of 7818 cases were analyzed. Prevalence of epithelial abnormalities was calculated in percentages.
Results: Of the 7818 pap smears studied, 7576 were satisfactory for evaluation. Among 165 (2.1%) cases showed epithelial cell abnormalities and 940(12.4%) were normal cases. Chronic white discharge per-vagina was the most common complain. LSIL was found to be the most common epithelial cell abnormality. Most abnormal pap smear findings were found in patients with white discharge per vaginum.
Conclusion: Incidence of invasive cervical malignancy can be prevented if PapSmear screening program is effectively implemented in target population.
References
- Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136:E359‑
- Bruni L, Barrionuevo‑Rosas L, Albero G, Aldea M, Serrano B, Valencia S, et al. ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases Reports 2015. Available from: http://www. hpvcentre.net/statistics/reports/XWX.pdf. [Last accessed on 2015 Mar 20].
- ICO Information Centre on HPV and Cancer. Human Papillomavirus and Related Diseases in India (Summary Report 2014‑08‑22); 2014.
- Anderson MC. The aetiology of cervical cancer. Female Reproductive System in Systemic Pathology.3rd ed., Vol. 6. New York: Churchill Livingstone; 1991. p. 76-9.
- Ansari M, Mehdi G, ArifSH, Ansari H, Khan T. Smear patterns and spectrum of premalignant and malignant cervical epithelial lesions in postmenopausal Indian women: A hospital‑based study. Diagn Cytopathol 2012;40:976‑
- Patel MM, Pandya AN, Modi J. Cervical pap smear study and its utility in cancer screening, to specify the strategy for cervical cancer control. Natl J Community Med 2011;2:49‑
- Bamanikar SA, Baravkar DS, Chandanwale SS, Dapkekar P. Study of Cervical Pap smears in a Tertiary Hospital. Indian Medical Gazette. 2014;250-254.
- Bhatla N, Gulati A, Mathur SR, Rani S, Anand K, Muwonge R, Sankaranarayanan R. Evaluation of cervical screening in rural North India. Int J Gynaecol Obstet. 2009;105(2):145-149.
- Vaghela BK, Vaghela VK, Santwani PM. Analysis of abnormal lcervical cytology in papanicolaou smears at tertiary care center – A retrospective study. IJBAR 2014;5:47‑
- Al Eyd GJ, Shaik RB. Rate of opportunistic pap smear screening and patterns of epithelial cell abnormalities in pap smears in Ajman, United Arab Emirates. Sultan QaboosUniv Med J 2012;12:473‑
- Sarma U, Mahanta J, Talukdar K. Pattern of abnormal cervical cytology in women attending a tertiary hospital. Int J Sci Res Publ 2012;2:1‑
- Verma A, Verma S, Vashist S, Attri S, Singhal A. A study on cervical cancer screening in symptomatic women using pap smear in a tertiary care hospital in rural area of Himachal Pradesh, India. Middle East FertilSoc J 2017;22:39‑
- Padmini CP, Indira N, Chaitra R, Das P, Girish BC, Nanda KM, et al. Cytological and colposcopic evaluation of unhealthy cervix. J Evid Med Healthc 2015;2:6920‑
- Idestrom M, Milsom I, Andersson-Ellstrom A. Knowledge and attitudes about the Pap-smear screening program: a population-based study of women aged 20-59 years. Acta Obstet Gynecol Scand. 2002;81(10):962-967.