Title: CBNAAT: Comparision of Diagnositc Yield in Sputum and Bal Fluid
Authors: Dr Santosh Kumar, Dr Gajendr Vikram Singh, Dr Avinash Kumar, Dr Parul Mittal, Dr Rishabh Goel
DOI: https://dx.doi.org/10.18535/jmscr/v7i7.25
Abstract
Aims and Objectives: To compare the diagnostic yield of CBNAAT method for BAL fluid and sputum for detection of mycobacterium to diagnose pulmonary tuberculosis.
Material and Methods: 129 sputum and BAL specimens from 129 patients were studied which included 65 specimens from sputum culture positive TB patients and 64 specimens from sputum culture negative patients. Patients with Sputum culture negative for MTB were considered as control.
Observation: It was observed that out of 65 culture positive cases of pulmonary tuberculosis, 43 were sputum CBNAAT (+)ve and 54 were CBNAAT (+)ve in BAL. Sensitivity and specificity of CBNAAT for sputum was 66.15% and 100% respectively. Sensitivity and specificity of CBNAAT for BAL was 83.07% and 100% respectively.
Conclusion: our study suggests that BAL-CBNAAT shows additional advantage of confirmatory diagnosis of the disease even if sputum CBNAAT is negative.
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