Title: Platelet Indices as Prognostic Markers in Sepsis Patients
Authors: Dr Rahul Gupta, Dr Harshal Pamecha
DOI: https://dx.doi.org/10.18535/jmscr/v7i4.07
Abstract
Introduction: Sepsis is a potentially life-threatening condition caused by the body's response to an infection. It is an extreme reaction to an infection that can, if untreated, be deadly. The objective of this research is to study the co-relation of various platelet indices in sepsis patients with their prognostic implications.
Methods & Materials: Various platelet indices were taken on day 1 and day 7 of admission for a total sample size of 117 patients with sepsis and a cross- sectional observational study was carried out using their hemogram reports succeeded by statistical analysis of their mean and standard deviation.
Results: The results showed a statistically significant difference in the Platelet count (PLT) and Plateletcrit (PCT) on observation day 1 and day 7 with no considerable statistical variations in Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Platelet Large Cell Ratio (PLCR) in the patients taken for the study.
Conclusion: The correlation of various platelet indices in patients with sepsis in the early stages of disease can be vital to plan and implement a targeted approach based on their prognostic implications.
Keywords: Sepsis, Hemogram, Prognosis, Platelet count, Plateletcrit, Mean Platelet Volume, Platelet Distribution Width, Platelet Large Cell Ratio.
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