Title: A study of Red Cell and Platelet Indices in acute myocardium infarction: A prospective study
Authors: Dr Shilpi Sikarwar, Dr Ajay Pal Singh
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.148
Abstract
Background: Platelets are known to be key factors of cardiovascular disease. Red cell indices and platelet volume indices are better indicators of acute myocardium infarction (AMI) and can play a major role in preventive measures of AMI.
Aims and Objective: To study the red cell indices and platelet indices in AMI.
Materials and Methods: One hundred and thirty seven AMI patients were studied. Diagnosis of AMI was confirmed by electrocardiogram (ECG) and Creatinine Phosphokinase-MB (CPK-MB) and patients were divided in to ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina. Platelet indices including mean platelet volume (MPV), Platelet large cell ratio (PLCR), platelet distribution width(PDW), plateletcrit (PCT) and red blood cells including Red Blood cell distribution width (RDW), mean corpuscular volume (MCV),mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC)were estimated for all the patients.
Results: Majority of the patients belong to age group of 50-69 years (57.65%) with male preponderance (62%).MPV(10.34 ±1.28) and PLCR(38.79 ±10.49) were significantly higher (P<0.0001) in ST-segment elevation myocardial infarction (STEMI) patient as compared to the non-ST-segment elevation myocardial infarction (NSTEMI) (MPV, 9.52 ±1.13; PLCR, 33.15 ±8.83) and unstable angina (MPV, 9.21 ±1.09; PLCR, 30.92±7.82). Mean RDW and MCHC was highest in STEMI patients while mean MCH and MCV was highest in NSTEMI subjects (P>0.05).
Conclusion: MPV, PDW and PLCR may be considered as prognostic markers for acute coronary syndrome.
Keywords: ST-segment elevation myocardial infarction, acute myocardial infarction, ECG.
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