Title: Evaluation of Carotid Intima Media Thickness as a Preclinical Atherosclerosis Marker in Diabetic Patients of North India

Authors: Dr Ram Asre, Dr Mridul Chaturvedi, Dr Balvir Singh, Dr Kushal Pal

 DOI: https://dx.doi.org/10.18535/jmscr/v6i12.115

Abstract

Objective: To evaluate carotid intima media thickness as a preclinical atherosclerosis marker in diabetic marker in diabetic patients.

Method: The study was conducted in PG Department of Medicine in Cardiology Unit, SN Medical College, Agra, Patients of any age group willing to take part in the study were included. Determination of Carotid intima media thickness (CIMT) was done by standard USG machine with high frequency probe.

Results: In our study the mean duration of diabetes was 5.7 years with SD of 4. The mean CIMT  in patients with diabetes of less than 5yrs (n=23) was 0.78 with SD of 0.07, while the mean CIMT in patients who have diabetes for more than 5 yrs is 0.87mm with SD 0.003. Using t test to compare the two groups, the p value was less than 0.001. This shows the impact of duration of diabetes with carotid intima media thickness and hence risk for atherosclerosis complication. Some patients in our study have short duration of diabetes but have high CIMT value which may be due to the late detection of diabetes.

Conclusion: CIMT measurements is an effective , noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to effectiveness of various treatment strategies used to treat people with diabetes.

Keywords: B-Mode USG,CIMT, Atherosclerosis, Diabetes.

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