Aim and Objective: The present study was undertaken to compare the combination of spinal (SA) and general anesthesia (GA) with plain general anesthesia (GA) in terms of heamodynamic parameters, requirement of rescue analgesia and incidence of post–operative nausea and vomiting (PONV).

Methods: In this study, 100 female patients of ASA grade I or II, having age between 20 to 60 years were randomly divided into two groups of 50 patients in each group. Group A received GA and group B received SA with GA. In group A induction of anaesthesia was done with propofol 2mg/kg and vecuronium bromide 0.1mg/kg while in group B induction was done with 15-18 mg of heavy bupivacaine hydrochloride. In both the groups, heamodynamic parameters (HR, SBP and DBP) and SPO2 were recorded and requirement of rescue analgesia were noted. Patients were monitored for any evidence of complications or adverse events.

Results: The heamodynamic parameters and VAS values were relatively lower in group B than group A and difference was found to be statistically significant (p< 0.05). Hence, the requirement of rescue analgesia was less in group B than group A. Group A had 70% of patients with PONV as compared to 28% in group B.

Conclusions: The combination of spinal and general anesthesia provided more stable hemodynamic profile with better postoperative pain control and less PONV in patients undergoing laparoscopic gynaecological surgeries.

Keywords: Spinal anesthesia, General anesthesia, Heamodynamics, Propofol, Vecuronium bromide, Bupivacaine hydrochloride.

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Dr Hemant Pawar

Dr. Vasantrao Pawar Medical College, Adgaon, Nashik Pin 422003