Abstract
Carcinosarcomas are highly malignant neoplasms where pleomorphic epithelial cells comingle with areas showing mesenchymal differentiation. Herewith, we describe the clinicopathological features of a case of carcinosarcoma gallbladder (CSGB). The patient was a female, aged 60 years. Immunohistochemical (IHC) examination revealed strong positivity of adenocarcinomatous tissue for cytokeratin while sarcomatous tissue showed vimentin antigen positivity. Findings of current case suggested differentiation of pluripotent tumor cells both as epithelial and mesenchymal components. She was diagnosed as a case of CSGB metastasizing in liver and a regional lymph node.
Keywords: Epithelial mesenchymal differentiation in a malignant neoplasm.
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Corresponding Author
Ashok Kumar Kapoor
RML Mehrotra Pathology Pvt Limited,
B 171, Nirala Nagar, Lucknow, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v5i10.184
