Background: Diabetes mellitus is one of the leading causes of morbidity and mortality. Studies have shown that hs-CRP is associated with insulin resistance, type 2 diabetes and higher HbA1c levels. This study was done to evaluate the correlation of hs-CRP with HbA₁C.

Objectives: The aim of this study is to determine the serum high sensitive C- Reactive Protein (hs-CRP) in patients with type 2 diabetes mellitus and to correlate with HbA₁C levels.

Materials and Methods: In this study 50 patients aged above 18 years with type 2 diabetes mellitus were enrolled and subjected to detailed history and examination. In all patients hs-CRP with HbA₁C were measured.

Results: In our study population 79% had hs-CRP levels ≥3.0 and 21% had hs-CRP levels <3.0. It concludes that higher prevalence of increase of hs-CRP in subjects with Type 2 diabetes. We found no statistically significant correlation among them except with duration of DM.

Conclusion: This study strongly warrants future investigations that probe the role of genetic variants and other environmental factors that influence the elevation of hsCRP levels in this high-risk group.

Keywords: HbA₁C, hs-CRP, Type 2 diabetes mellitus.

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Himanshu Devender Kumar

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