Title: Evaluation of Anemia among Deferred Prospective Blood Donors at Kenyatta National Hospital, Kenya
Authors: Njenga Kariuki John, Kahato Michael Ngugi, Valerie Magutu, Wacuka Njoroge
Introduction: Blood transfusion has over the years saved millions of lives around the world. However, majority of developing countries are not in a position to meet the high demand for blood in its hospitals. A large number of donor deferrals are pre-donation, temporary deferrals being the most common with anemia as a leading cause. Anemia is a potentially treatable and preventable cause of temporary deferral It is, therefore imperative to study low hemoglobin (anemia) among deferred donor population to enable development of mitigation measures and ultimately increase blood supply. The main objective of this study was to evaluate anemia among deferred anemic prospective blood donors at Kenyatta National Hospital.
Methodology: Descriptive cross–sectional study of 138 participants was assessed for anemia using point of care hemoglobin analyzer (Stat-Site® MHgb). Three (3) ml EDTA venous blood sample was collected and analyzed for hemoglobin and red blood cells indices using automated hematology analyzer (Sysmex) and peripheral blood film.
Results: Low hemoglobin deferral accounted for 162 (10.1%) using point of care hemoglobin analyzer. Three types of anemia were identified among the participants; normocytic normochromic (72.7%), microcytic hypochromic (15.9%) and normocytic hypochromic (6.8%).
Conclusion: A signicant number 96 (69.6%) of prospective blood donors deferred of low Hb by POC analyzer were found not to be anemic using standard methods. This study recommends urgent remedies should be sought to address lose of prospective blood donors due to variation in hemoglobin screening by hemoglobin analyzers and review of donor hemoglobin cut-off value.
Keywords: Donor deferrals, hemoglobin, blood donors.