Abstract
Lingual thyroid is relatively uncommon developmental defect of thyroid gland embryogenesis. We report a case of 48 year-old female patient who presented to us with swellings in both side of neck since 2 years. She was diagnosed follicular variant of papillary carcinoma of lingual thyroid with nodal metastasis and absent orthotopic thyroid tissue . Till date less than 50 cases of lingual thyroid carcinoma have been described inthe international literature .To the best of our knowledge ,less than 3 cases of this variant have been reported. Treatment was managed with surgical excision of all thyroid tissue followed by radioactive iodine ablation and levothyroxine therapy. This case report provides current understanding about the clinical spectrum of this rare condition, also referring to optimal diagnostic approach including role of MRI and management strategies.
Key-words: Follicular variant, Papillary Carcinoma, Lingual Thyroid , Neck Metastasis
References
1. Di Benedetto V. Ectopic thyroid gland in the submandibular region simulating a thyroglossal duct cyst: a case report. Journal of Pediatric Surgery 1997 32 1745–1746. (doi:10.1016/S0022-3468 (97) 90522-4)
2. Singh HB, Joshi HC, Chakravarty M. Carcinoma of the lingual thyroid. Review and case report. J Laryngol Otol 1979;93:839-44
3. Fish J MR. Ectopic thyroid tissue and ectopic thyroid carcinoma: a review of literature and report of a case. Ann Surg 1963;157:212-22
4. Massine R, Durning S, Koroscil T. Lingual Thyroid Carcinoma: A Case Report and Review of the Literature. Thyroid 2001; 12 (11): 1191-1196
5. Talwar N, Mohan S, Ravi B, Andley M & Kumar A. Lithiuminduced enlargement of a lingual thyroid. Singapore Medical Journal 2008 49 254–255.
6. Mishriki YY, Lane BP, Lozowski MS & Epstein H. Hu¨ rthle-cell tumor arising in the mediastinal ectopic thyroid and diagnosed by fine needle aspiration. Light microscopic and ultrastructural features. Acta Cytologica 1983 27 188–192.
7. American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM: Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009, 19(11):1167–1214.
8. Grossman A, Olonovski D & Barenboim E. Hypothyroidism caused by a nonvisible lingual thyroid. Head and Neck 2004 26 995–998. (doi:10.1002/hed.20123)
9. Toso A, Colombani F, Averono G, Aluffi P & Pia F. Lingual thyroid causing dysphagia and dyspnoea. Case reports and review of the literature. Acta Otorhinolaryngologica Italica 2009 29 213–217.
10. Farrell ML & Forer M. Lingual thyroid. Australian and New Zealand Journal of Surgery 1994 4 135–138.
Corresponding Author
Dr Bharat Gupta
PG Boys Hostel, R.N.T. Medical College, Udaipur (Raj)
INDIA Pin Code: 313001
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mobile No. : +919783417878
DOI: http://dx.doi.org/10.18535/jmscr/v4i2.26
