Co-Morbidity of Pulmonary Tuberculosis and Diabetes Mellitus-A Prospective Analysis

Title: Co-Morbidity of Pulmonary Tuberculosis and Diabetes Mellitus-A Prospective Analysis

Authors: Dr Ajith Kumar.M.K, Dr Rajani.M, Dr Manoj.D.K, Dr Saraladevi.A., Dr Achuthan.V

DOI: http://dx.doi.org/10.18535/jmscr/v4i3.52

Abstract

References

Corresponding Author

Abstract

Several studies have evaluated the relationship between diabetes mellitus (DM) and tuberculosis (TB), but the nature of this relationship is not fully understood. TB incidence may be influenced by immune suppression from DM, but this association may be confounded by other clinical and socioeconomic factors. We aimed to assess socio-demographic and clinical differences in TB patients with and without DM.A semi- Structured Proforma was used to collect the socio-demographic profile & clinical features, including the age, the sex, the site of the tuberculous pulmonary involvement seen on the chest roentgenogram of the patients. A fasting value >/= 129 mg/ dl & 2hrPPBS >/= 200 mg/ dl was considered as diabetes mellitus. Comparison of the clinical features was conducted after dividing them to 2 groups: - namely Group A (patients with sputum AFB positive tuberculosis and diabetes mellitus) & Group B (patients with sputum AFB positive tuberculosis without diabetes. Males were more affected than females. Most common age group affected was 51-60(52.05%). Out of 73 patients, 49 (67.1%) had the history of contact with tuberculosis. The presence of diabetes mellitus was found not to have a statistically significant effect on the patients’ symptoms. DM and TB represent a critical intersection between communicable and non-communicable diseases in these countries and the effect of DM on TB incidence and outcomes provide numerous opportunities for collaboration and management of these complex diseases in the national public health programs.

Keywords: Diabetes Melitus, Tuberculosis

References

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