Antibiotics Susceptibility Profile of E.Coli in Female Students of University of Agriculture Makurdi

Title: Antibiotics Susceptibility Profile of E.Coli in Female Students of University of Agriculture Makurdi

Authors: Yaji, M.E. Gberikon, G.M., Okpe.L

DOI: http://dx.doi.org/10.18535/jmscr/v4i3.16

Abstract

References

Corresponding Author

Abstract

A study to determine antibiotic susceptibility profile of E.coli urinary tract infection among female students of University of Agriculture, Makurdi was under- taken. A total of 100 early mornings, mid -stream urine samples were collected and cultured on Cystein Lactose Electrolyte Deficiency (CLED) and Eosine Methylene Blue (EMB). Out of the 100 samples, 48 had growth. E.coli was 25%, Staphylococcus aureus 9%, Candida albicans 8%, Klebsiellaspp 4%, Pseudomonas and Proteus spp 2.1%. E.coli had the highest percentage while proteus and Pseudomonas had the lowest. However it was not statistically significant. Antibiotic susceptibility test by disc diffusion method indicated that , the most effective antibiotics was gentamycin with 92%,while the most resistant was septrin with 16%. Others were Ciprofloxacin 76%, ofloxcin 60%, sperfloxacin 24%, amoxicillin24%, and chloramphenicol 16%. E.coli is a common etiologic agent of urinary tract infection (UTI) among female students in University of Agriculture, Makurdi and its antibiotics susceptibility profile indicates that UTI caused by E.coli can be effectively treated.

References

1. Akinjogunla, O. J, Odeyemi, A. T, and Olasehinde, G. I (2010). Epidemiological Studies of Urinary Tract Infection (UTI) among Post-menopausal Women in Uyo Metropolis, South-South, Nigeria. Journal of American Science; 6(12).

2. Amdekar, S; Singh, V, Singh, DD (2011). "Probiotic therapy: immunomodulating approach toward urinary tract infection. ".Current microbiology 63 (5): 484–90.

3. Ani, o. c (2008) . Prevalence of urinary tract infections (UTI) in sexually active women of Abakaliki, Ebonyi State, Nigeria. Animal Research International . 5(2): 876 – 879 .

4. ANON (2006).Urinary tract infections in women.http://familydoctor.og/online/famdocen/home/women/genhealth/190/html

5. Asad U Khan and Mohd S Zaman (2012) . Multiple drug resistance pattern in Urinary Tract Infection patients in Aligarh biomedical research; 17 (3): 179-181.

6. Calderon CB, Sabundayo BP (2007). Antimicrobial Classifications: Drugs for Bugs. In Schwalbe R, Steele-Moore L, Goodwin AC. Antimicrobial Susceptibility Testing Protocols.CRC Press.Taylor & Francesgroup.ISBN978-0-8247-4100-623.

7. Cheesbrough M (2000). District Laboratory Practice in TropicalCountries. 5^th Edition, Cambridge United Press, U.K.27 pp.

8. Dienye, P.O., Gbeneol, P.K (2011). Contraception as a Risk Factor for Urinary Tract Infection in Port Harcourt, Nigeria: A Case Control Study. African Journal Of Primary Health Care Family Medicine; 12(4): 220-230.

9. Dimitriv TS, udo EE, Emara M, Awni F, Passadilla R (2004). Etiology and antibiotic in central, Madagascar :Uropian Journal Of Rural Community Health Care. 13(7): 80-88.

10. Dorlands Medical Dictionary: antibacterial". Archived from the original on 2010-11-17.Retrieved 2010-10-29.

11. Dorlands Medical Dictionary:antibiotic". Archived from the original on 2010-11-17.Retrieved 2010-10-29.

12. Duerden B .I, Reid TMS, Jewsbury J . M, Turk DC (1990). UTI risk factors .A New Shortbook of Medical Parasite. 7^th edition, Baltmore:Lippicott Williams and Wilkins. 175 pp.

13. Feng P, Weagant S, Grant, M (2002-09-01). "Enumeration of Escherichia coli and the Coliform Bacteria". Bacteriological Analytical Manual (8th ed.). FDA/Center for Food Safety & Applied Nutrition. Retrieved 2007-01-25.

14. Gruneberg RN (1994). Changes in urinary pathogens and their antibiotic sensitivities.J AntimicrobChem-other ; 33: 1-8.

15. Jombo , G.T, Egah , D.Z , Banwat , E.B , Ayeni, J.A (2006). Nosocomial and Community Jombo acquired Urinary Tract Infections at a Teaching Hospital in North Central Nigeria: findings from a study of 12,458 urine samples. Nigerian Journal of Medicine, 15(3):230-6

16. KarlowskyJ .A, Jones M.E, Thornsberry C, Critchley, I, Kelly L, Sahm D (2001). Prevalence of antimicrobial resistance among pathogens isolated from female outpatients across the US in .Int J AntimicrobAgents ; 18: 121-127.

17. LATIF, A. S (2004).Urogental infections in the tropics.Pages. In: LATIF, A. S and SPINGS, A. (Eds). STI/HIV project.The Australasian College of Tropical Medicine Publishing Press, Harare. 60pp.

18. MACNAIR, I (2006). Urinary Tract infection http://www.bbc.co.uk/health/conditions/urinarytract2.shtml

19. Mathai D, Jones R.N, Pfaller M .A (2001) Epidemiology and frequency of resistance among pathogens causing urinary tract infection in 1,510 hospitalized patients: a report from the SENTY Antimicrobial Surveillance Program (North America) DiagMicrobiol Infect Dis; 40: 129-136.

20. MERCOLA, J (2001). Cranberry juice for urinary tract infections.Bitish Medical Journal, 322: 1571 –

21. National Committee for Clinical Laboratory Standards (NCCLS)( 2000). Methods for dilution isolate for antimicrobial susceptibility tests for bacteria that grow aerobically: Approved standard – 5th edn. NCCLS document M7-A5 (ISBN 1-56238-394-9) NCCLS. Wayne, Pennsylvania 19087-1898, USA.

22. National Committee for Clinical Laboratory Standards (1999).Performance standards for antimicrobial susceptibility testing.Ninth informational supplement. 18, number 1. Wayne, Pa: National Committee for Clinical Laboratory Standards.

23. Obiogbolu, C. H, Okonko, I. O, Anyamere, C. O, Adedeji, A. O, Akanb,i A. O , Ogun, A. A, Ejembi, J. and Faleye, T. O. C (2009).Incidence of Urinary Tract Infections (UTIs) among pregnant women in Akwa metropolis, Southeastern Nigeria. Scientific Research and Essay . 4 (8).8

24. Willey, L .S, Chris Woolverton (2013) . Antimicrobial Chemotherapy. Microbiology , 13th Edition,McGraw-Hill Book. Htt://create.mcgraw-hill.com. 195pp.

25. Willey, L .S, Chris Woolverton (2013) . Development of Antibiotic Resistance in Bacteria .Microbiology, 13th Edition, McGraw-Hill Book. Htt://create.mcgraw-hill.com. 398pp.

26. SA Waksman (1947). "What Is an Antibiotic or an Antibiotic Substance?".Mycologia 39 (5): 565–569.

27. Salvatore, S, Salvatore, S, Cattoni, E, Siesto, G, Serati, M, Sorice, P, Torella, M (2011). "Urinary tract infections in women.". European journal of obstetrics, gynecology, and reproductive biology 156 (2): 131–6.

28. Stamm W.E, Hooton T.M (1993) .The management of urinary tract intections.N Engl J Med ; 329: 1328-1334.

29. Thompson, Andrea (2007). "E. coli Thrives in Beach Sands". Live Science. Retrieved .06/04/2007.

30. THOMPSON, T (2006). Urinary Tract Infection Medication: Antibiotics for UTI. http://www.nativeemedies.com/articles/urinary-tract-infection-medication-antibioticsuti. html.9

31. Todar, K (2007) ."Pathogenic E. coli".Online Textbook of Bacteriology. University of Wisconsin–Madison Department of Bacteriology. Retrieved Infection. ELBS Publishers.576-582.

32. Todar, K. (2010). Pathogenic E. coliInTodar's Online Textbook of Bacteriology. Retrieved from http://www.textbookofbacteriology.net/e.coli_4.html

33. Von Nussbaum F (2006). "Medicinal Chemistry of Antibacterial Natural Products – Exodus or Revival?".Angew. Chem. Int. Ed. 45 (31): 5072–5129.

34. Warren J.W, Abrutyn E, Hebel J.R, Johnson J.R, Schaeffer A.J, Stamm W.E (2007).Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystis and acute pyeloephritis in women. Clin Infect Dis 199; 29: 745-758.

35. Willey, L.S Chris Woolverton (2013) . Antimicrobial Chemotherapy. Microbiology, 13th Edition,McGraw-Hill Book. Htt://create.mcgraw-hill.com. 189pp

36. Witte W (2004). "International dissemination of antibiotic resistant strains of bacterial pathogens".Infect. Genet.Evol. 4 (3): 187–91.

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