Abstract
Now-a-days, fluorosis is one of the important public health problems in many regions of Indian subcontinent. The present cross-sectional observational study had been undertaken at Simlapal block, one of the fluoride endemic zones of Bankura district, West Bengal, India to evaluate the relationship between thyroid hormone status and serum fluoride level among the tribal population. This study was carried on 67 fluorosis cases. Serum samples were collected from the cases and serum fluoride level was estimated by Ion-Meter and serum Thyroid stimulating hormone (TSH), free Triiodothyronine (fT3) and free Thyroxine (fT4) levels were measured by ELISA method. It was observed that there was a female preponderance in hypothyroidism compared to the male subjects who were suffering from fluorosis. This study also exposed that out of 67 cases 12 (ie, 17.91%) were suffering from hypothyroidism.
Keywords- Fluorosis, Serum fluoride, TSH, fT3, fT4
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DOI: http://dx.doi.org/10.18535/jmscr/v4i6.76
