Objectives:  To evaluate the utilization of Probiotics and Racecadotril for the patients of acute gastroenteritis (AGE) and subsequently their health outcome at an Infectious Disease Hospital and to observe the relationship among demographic profile of the patients as well as antisecretory consumed exerting impact on AGE .                                                                                                           

Materials and Methods:  A retrospective study was undertaken collecting total 459 patient’s data from patient admission ticket of an infectious disease hospital. Mainly drugs used and outcome of the patients were recorded. Of all patients 190 were found to be treated with fluid and probiotics, 150 with fluid plus probiotics plus ofloxacin and ornidazole, 49 with fluid plus racecadotril, 40 with fluid plus racecadotril plus oflxacin and ornidazole and only 30 patients got fluid plus ofloxacin and ornidazole. Data were statistically analyzed in respect of demographic profile, drugs used and clinical features of the patients. 

Results: Best outcome was observed in patients treated with fluid and probiotcs where 189 patients were cured. 146 out of 150 patients got cured with ofloxacin and ornidazole in addition. All 49 patients having racecadotril and fluid recovered. Fluid plus racecadotril plus ofloxacin and ornidazole cured 38 of 40 patients. 27 of 30 patients were cured with fluid plus ofloxacin and ornidazole.

Conclusion:  Probiotics and antisecretory agents like Racecadotril are costly but are very effective along with fluid and electrolyte to prevent AGE.

Key Words:   Gastroenteritis, probiotics and racecadotril.