Title: Comparative Study of Rapid Diagnostic Test Versus Elisa For HIV Detection At Blood Bank In Tertiary Care Hospital
Authors: Dr Parth R.Goswami, Dr Jitendra J. Chavda
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.29
BACKGROUND: Human immunodeficiency virus leads to development of AIDS which is one of the major public health problem worldwide.1,2 So it is necessary to diagnose HIV as early as possible for prevention of HIV spread in community AIM: This study help us to evaluate effectiveness of rapid diagnostic kits as compared to ELISA methods. MATERIALS AND METHODS: This study was carried out at tertiary care hospitals (blood bank),Gujarat , India from the date 01/01/2016 to 31/07/2016.We have tested total 9111 donor samples with using fourth generation ELISA kit as well as Rapid diagnostic kit. RESULTS: Rapid diagnostic tests having Sensitivity of 90.90%. specificity was 100%,positive predictive value 100% and negative predictive value 99.98%. and accuracy was 99.98% . CONCLUSION: The rapid diagnostic HIV kits assay gives result in 15 minute can be used in emergency situations when there is less time available to perform ELISA test. So as sensitivity and specitivity of rapid diagnostic tests are high it can be used in emergency situation whenever needed KEYWORDS: ELISA, Human immunodeficiency virus, p24 antigen, Rapid diagnostic test.
Abstract