Title: Clinicopathological profile of salivary gland swellings in Kumaon region of Uttarakhand
Authors: Dr Bhawana Pant, Dr Sanjay Gaur, Dr Binay Kumar, Dr Deepa Arya
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.13
Aim/Objective: The objective of this study was to evaluate the various salivary gland lesions in Kumaon region of Uttarakhand. Materials and Methods: A total of 200 patients with salivary gland lesions were evaluated from Jan 2008 to June 2016. FNAC was performed on these patients at department of Pathology in Government Medical college Haldwani. Patients were received from ENT, medicine and surgery departments after proper clinical, hematological and radiological evaluation. Surgically resected, formalin fixed specimen were also received, they were processed and slides were prepared. The cytological and histopathological stained slides were studied, analyzed and correlated. Results: FNAC of 200 cases were studied and following results were observed. Out of 200 patients included in the study the different categories of salivary gland lesions incuded benign,malignant and non neoplastic. Non neoplastic lesions constituted 103 cases(51.5% ) and included conditions like acute or chronic infection, calculus and cystic lesions etc. Rest (97) were neoplastic conditions which included benign and malignant lesions. Benign lesions constituted 69 cases (34.5% ) while malignant lesions seen in 28 cases(14% ). Parotid was the most common major salivary gland to be involved(57% ). Out of 97 cases cyto-hitological correlation could be done in only 60 cases. Only 50 cases were correctly diagnosed. 10 cases had no correlation between cytology and histopathological finding. . In the present study sensitivity of FNAC for diagnosis of malignant lesions was 85%, specificity of 93.02% , negative predictive value of 93.02%, positive predictive value of 85% and diagnostic accuracy of 83.33%. Conclusion: FNAC of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although it has a high diagnostic accuracy, rate of characterization of specific type of tumor is low due to variable cytomorphology. In such cases, histopathological examination may prove to be accurate for diagnosis.
Abstract
