Title: To Study Correlation between Serum Vitamin D3 Deficiency with Individual Parameters of Metabolic Syndrome and Left Ventricular Ejection Fraction in Coronary Angiographically Proven Coronary Artery Disease Patients At Central India
Authors: Dr Dharmendra Kumar Mekle, Dr Jeetandra Kumar Sharma
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.98
Vitamin D is thought to alter cholesterol metabolism and calcium metabolism, modulate immune system, impair inflammation, associated with insulin resistance and metabolic syndrome. thats why aim of the study was to study correlation between vitamin D deficiency with metabolic syndrome and left ventricular ejection fraction in coronary artery diseased patients. METHODS: This was an observational cross-sectional study which was carried out in consecutive 60 coronary artery disease patients from OPD and ward from Department of Cardiology, Gandhi medical college and associated Hamidia hospital Bhopal from november 2011 to December 2012. RESULTS: Statistically Significant correlation between CASES and CONTROLS for vitamin D3 deficiency with mean blood pressor, HDL, triglycerides, fasting blood sugar, left ventricular ejection fraction (p-<0.01) except waist circumference. In present study Vitamin D had direct correlation with EF% in Echocardiography (Correlation coefficient = 0.268, p value = 0.000000) and HDL (Correlation coefficient=0.422,p=0.000000) and inverse correlation with other parameters. CONCLUSION: Vitamin D deficiency may provoke metabolic syndrome, athermanous plaque formation and establish coronary artery disease. KEY WORDS : Vitamin D Deficiency, Metabolic Syndrome
Abstract
