Metastatic MalignantMelanoma of Gastrointestinal Tract with Unknown Primary- A Diagnostic Dilemma?

Title: Metastatic MalignantMelanoma of Gastrointestinal Tract with Unknown Primary- A Diagnostic Dilemma?

Authors: Padhi Sanjukta, Pujari Lincoln, Meher Papuji, Samantray Sagarika, Singh Sivram Prasad

DOI: http://dx.doi.org/10.18535/jmscr/v4i8.87

Abstract

References

Corresponding Author

Abstract

Background: Malignant melanoma with its diverse histological patterns and varied manifestations is a diagnostic enigma. This problem becomes even more complex when it presents as a metastatic lesion with no known primary site. This is referred to as malignant melanoma of unknown primary (MUP). MUP generally accounts for 2-9% of all melanomas ⁽¹⁾. The incidence of malignant melanoma in the gastro-intestinal tract without any evidence of a primary lesion in the skin or any other site is extremely rare ^{(2, 3)}

Case: We present here a case of a 58 yr old man with symptoms such as vomiting,epigastric pain and loss of appetite for two months. General examination revealed a right inguinal lymphadenopathy and hepatomegaly with no abnormality in skin. On endoscopic evaluation we found, multiple melanotic patches on gastric mucosa, .Metastatic melanoma in stomach with unknown primary is a rare entity and we report it here for documentation.

Conclusion: Metastatic malignant melanoma of the gastrointestinal tract without an identifiable source is exceptionally rare. The present case puts light into the extensive search and timely diagnosis to yield a early pre-mortem diagnosis and timely intervention.

Keywords: MUP, Gastric Melanoma, Diagnosis.

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