Title: Silver Stained Nucleolar Organising Region (AgNOR) Count and its Correlation with Colposcopy in Suspicious Cervical Pathology
Authors: A.R.Nasreen Fathima, S.Thangathai
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.68
Introduction: Colposcopy is considered a sensitive tool for screening of cervical malignancy. Colposcopy directed biopsy helps in confirming diagnosis. Silver stained nucleolar organising region (AgNOR count) of dysplastic cells further enhances the diagnosis. Aim: To study the correlation of AgNOR count and colposcopy in suspicious cervical lesions. Materials and methods: 200 women of reproductive age group were screened for cervical cancer and colposcopy directed biopsy taken. AgNOR count studied and correlated with HPE and Modified Reid’scolposcopic index. Results: There was a good correlation between AgNOR count and the degree of dysplasia. Also there was a good correlation of AgNOR count and Modified Reid’scolposcopic index. Conclusions: AgNOR count is simple, effective method and it adds strength to histopathology and colposcopy and also assess different grades of cervical intraepithelial neoplasia. Keywords: colposcopy, cervical intraepithelial neoplasia, AgNOR count, Reid’s colposcopic index.
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