Wound infection continues to be a challenging problem and represents a considerable healthcare burden. A study was conducted in Government Medical College Kota (Rajasthan) to study the incidences of wound infection in perforation cases. Total 100 patients of Peptic and Enteric perforation were included in this study. In this study incidence of wound sepsis in peptic perforation was 16.12% and in Enteric perforation was 31.57%. E.coli was found responsible in 68% of cases and Staph. Aureus was found in 18% of cases while Klebsiella sp. was identified in 14% of cases. When peritoneal lavage has been done by local antibiotics plus normal saline, wound sepsis was present in 15% of cases compared to 40% of with normal saline plus Povidone iodine and 20% of cases with normal saline alone. Piperacillin-Tazobactam is sensitive in 86.36% of wound sepsis cases whereas Aminoglycosides were found sensitive in 45.45% and Fluroquinololes were found sensitive in 31.81% of cases.

Keywords: Peptic, Enteric, Wound infection.