Title: Assessment of Cognitive Function in 36 Type 2 Diabetic Women in Erbil City
Author: Yousif Baha’addin Ahmed
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.08
Background: Recent evidence from several epidemiological studies suggests that diabetes is a risk factor for cognitive dysfunction, Diabetes is associated with a 1.5 to 2 fold increased risk of dementia, This has been explained by secondary diabetic encephalopathy which occurs as a result of micro- and macro-vascular disorders or due to repeated episodes of hypoglycemia induced by excess insulin, It is important to assess the effect of diabetes on cognitive function, a part from chronic complications and co-morbidities. Subjects and methods: This cross sectional controlled study was carried out at Rezgary and Erbil teaching hospitals in Erbil city. A total of 36 Apparently healthy women were recruited and used as a control group for comparison, A total of 36 type 2 diabetic women without co-morbidities and with no apparent chronic complications of diabetes were recruited, The subjects were fasting, their cognitive function was assessed using mini-mental state examination score, fasting plasma glucose measurement and estimation of glycosylated hemoglobin (HbA1c) done for diabetic patients and fasting plasma glucose estimated for control group. Results: The mean fasting plasma glucose of diabetics was 213.78 mg/100ml and that of control subjects was 95.67 mg/100ml. The mean mini-mental state examination score for diabetics was 17.53 and for control group was 17.56. There was no correlation between mean HbA1c and mean mini-mental state examination score of diabetics, Also no correlation found between duration of the disease and cognitive function. Conclusions: 1-Uncomplicated diabetes without co-morbidities does not cause declining cognitive function 2-There is no correlation between cognitive function and glycemic control in type 2 diabetic patients Keywords: dementia-glycemia, glucose-mental state.
Abstract
