Abstract
Introduction
Epilepsy and Migraine are the chronic disorders with recurrent neurological dysfunction associated with headache and autonomic, abdominal and psychotic features. In some patients it may be difficult to differentiate between migraine and the seizure episodes. Both are having comorbid symptoms and occurrence. Migraine patients can develop seizure and epileptics can have migraine attacks. Epileptologists proposed the hyperexcitability of the altered brain tissue, as the cause of seizure and migraine headache occurrence and vice versa. Enhanced hyperexcitability of cortical neurons and diminished threshold are the pathophysiological mechanisms enumerated in these conditions. Low magnesium in brain and the altered neurotransmitters are responsible for increased cortical excitability. Both the environmental as well as the genetic factors might cause these changes.
References
- Andermann E, Andermann Migraine-epilepsy relationships: epidemiological and genetic aspects. In: Andermann FA, Lugaresi E, editors. Migraine and Epilepsy. Boston: Butterworths; 1987. pp. 281–291.
- Patrick wan, celesteB.L.Man, Howanleung et al. Headache in patients with epilepsy:A prospective incidence study.division of neurology,The Chinese university of Hongkong, Epilepsia,1-4, 2008doi:10.1111/j.1528- 167.2008.01574.
- Multi-center study on Migraine and Seizure-related headache in patients with epilepsy-HELP(Headache in Epilepsy Group)study group; Yonseimedj, >v.51(2)Mar1, 2010>pmc 2824867
- Ito M, Nakamura F, Honma H, Takeda Y, Kobayashi R, Miyamoto T, et al. A comparison ofpost-ictal headache between patients with occipital lobe epilepsy and temporal lobe epilepsy. Seizure. 1999; 8:343–346.
- Ito M, Schachter SC. Frequency and characteristics of interictal headaches in patients with epilepsy. J Epilepsy. 1996;9:83–86.
- Ito M, Nakamura F, Honma H, Takeda Y, Kobayashi R, Miyamoto T, et al. Clinical factors associated with post-ictal headache in patients with epilepsy. ActaNeurol Scand. 2000;102:129–131.
- Forderreuther S, Henkel A, Noachtar S, Straube A. Headache associated with epileptic seizures: epidemiology and clinical characteristics. Headache. 2002;42:649–655.
- Leniger T, Isbruch K, von den Driesch S, Diener HC, Hufnagel A. Seizure- associated headache in epilepsy. Epilepsia. 2001;42:1176–1179.
Corresponding Author
Dr Sourav Chattopadhyay
PDT, Deptt. of Neurology, Geetanjali Medical College and Hospital, Hiranmagri Extension, Manwakhera NH- 8 Bypass, Near Eklingpura Chouraha, Udaipur 313002, Rajasthan, India